SCHEMBL4390894

SCHEMBL4390894

O=C(Cc1ccccc1[N+](=O)[O-])Oc1cc2ccccc2oc1=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.57
MAOA P21397 2/20 0.47
MGAM O43451 1/20 0.44
GAA P10253 1/20 0.44
SI P14410 1/20 0.44
MGAM2 Q2M2H8 1/20 0.44
POLB P06746 1/20 0.43
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
MAPT P10636 4/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MAOB P27338 1/20 0.42
ACHE P22303 2/20 0.42
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 1/20 0.41
GLA P06280 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10404821 0.76 L3MBTL1 (0.56) GAAMEN1KMT2AMAPTKDM4E
SCHEMBL17898567 0.75 LMNA (0.48) APPGAAMEN1KMT2AMAPT
SCHEMBL7537579 0.75 POLB (0.54) MAOAPOLBMEN1KMT2ASMN1; SMN2
SCHEMBL1046782 0.74 MAOA (0.54) MAOAMGAMGAASIMGAM2
Acetic Acid SCHEMBL29797062 0.72 MAOB (0.55) MAOAMGAMGAASIMGAM2
SCHEMBL10404712 0.72 MEN1 (0.52) APPMEN1KMT2AMAPTSMN1; SMN2
SCHEMBL1045399 0.72 KDM4E (0.61) MAOAPOLBMEN1KMT2ASMN1; SMN2
SCHEMBL6036799 0.72 MAOB (0.58) MAOAPOLBMEN1KMT2ASMN1; SMN2
SCHEMBL3291386 0.71 ALDH1A1 (0.56) POLBMEN1KMT2AMAPTSMN1; SMN2
SCHEMBL31379000 0.71 ALDH1A1 (0.56) POLBMEN1KMT2AMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629400-B2 Image making medium HYMAN SYDNEY 2009-12-08 US disclosed
US-20030035917-A1 Image making medium HYMAN SYDNEY (US) 2003-02-20 US disclosed