Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 14/20 | 0.84 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | GLI1 | P08151 | 1/20 | 0.42 |
| ▸ | GLI2 | P10070 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010536 | 0.88 | HTR7 (0.84) | HTR7 | |
| SCHEMBL17560828 | 0.79 | HTR7 (0.70) | HTR7EGFR | |
| SCHEMBL15131079 | 0.73 | OPRK1 (0.65) | MEN1KMT2AOPRK1EGFRGLI1 | |
| SCHEMBL13632558 | 0.72 | HTR7 (1.00) | HTR7 | |
| SCHEMBL4372674 | 0.71 | NUDT1 (0.47) | HTR7MEN1KMT2AOPRK1EGFR | |
| SCHEMBL7006872 | 0.70 | HTR7 (0.81) | HTR7 | |
| SCHEMBL10964333 | 0.70 | HTR7 (0.59) | HTR7 | |
| SCHEMBL4375461 | 0.69 | HTR7 (0.58) | HTR7EGFR | |
| SCHEMBL21593091 | 0.69 | HTR7 (0.58) | HTR7EGFR | |
| SCHEMBL16343362 | 0.69 | HTR7 (0.62) | HTR7EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1280781-B1 | 5-HT 7 RECEPTOR ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2009-11-18 | — | — | EP | claimed |