Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4391732 | 0.81 | ALDH1A1 (0.51) | KDM4ECYP2D6CYP3A4CYP1A2MEN1 | |
| SCHEMBL8938637 | 0.73 | SIGMAR1 (0.51) | MAPK1SLC6A2SLC6A3CYP2D6CHRM2 | |
| SCHEMBL5656404 | 0.72 | NPC1 (0.43) | ADRA1AMEN1KMT2A | |
| SCHEMBL3784355 | 0.72 | SIGMAR1 (0.44) | SLC6A2SLC6A3HTR1ASLC6A4MEN1 | |
| SCHEMBL4889326 | 0.69 | MEN1 (0.43) | CYP2D6CHRM2HTR1ACHRM1ADRA1A | |
| SCHEMBL1299631 | 0.69 | SIGMAR1 (0.52) | KDM4EMAPK1SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL8499574 | 0.69 | PRMT5 (0.48) | OPRM1KCNH2LMNA | |
| SCHEMBL5774496 | 0.69 | TSHR (0.41) | MAPK1CYP2D6CHRM1CYP3A4KMT2A | |
| SCHEMBL11402064 | 0.69 | SLC6A3 (0.51) | KDM4EMAPK1SLC6A2SLC6A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL1299136 | 0.68 | SIGMAR1 (0.51) | KDM4EMAPK1SLC6A2SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005309-A1 | SUBSTITUTED PIPERIDINES | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-01-01 | — | — | US | disclosed |
| WO-2008144602-A1 | DEUTERATED ZAMIFENACIN DERIVATIVES | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005309-A1 | SUBSTITUTED PIPERIDINES | CHRM3, CHRM2, CHRM5 | KDM4E 2817/4885MAPK1 2826/4885SLC6A2 1210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.