SCHEMBL4392002

SCHEMBL4392002

Nc1cccc(-c2ccccc2C(F)(F)F)c1N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.42
HSD11B1 P28845 3/20 0.42
ALDH1A1 P00352 4/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
POLB P06746 2/20 0.41
GLA P06280 1/20 0.41
GAA P10253 1/20 0.41
TSHR P16473 1/20 0.41
CES1 P23141 1/20 0.41
BACE1 P56817 1/20 0.41
NOTUM Q6P988 1/20 0.40
MPL P40238 2/20 0.39
TDP1 Q9NUW8 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
ALOX15 P16050 1/20 0.38
MAPK1 P28482 1/20 0.38
CYP2C19 P33261 1/20 0.38
HSD17B10 Q99714 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL397945 0.85 ALDH1A1 (0.59) HSD11B1ALDH1A1L3MBTL1POLBGLA
SCHEMBL16340864 0.85 HSD11B1 (0.44) PDK2HSD11B1ALDH1A1L3MBTL1POLB
SCHEMBL3789801 0.84 ALDH1A1 (0.52) PDK2HSD11B1ALDH1A1L3MBTL1POLB
SCHEMBL28527850 0.82 TSHR (0.39) PDK2ALDH1A1L3MBTL1POLBGLA
SCHEMBL476347 0.81 CD44 (0.42) PDK2ALDH1A1L3MBTL1POLBGLA
SCHEMBL16414055 0.81 MPL (0.44) PDK2HSD11B1ALDH1A1L3MBTL1POLB
SCHEMBL29589903 0.81 CD44 (0.42) PDK2ALDH1A1L3MBTL1POLBGLA
SCHEMBL197671 0.80 HSD11B1 (0.56) HSD11B1ALDH1A1L3MBTL1POLBNOTUM
SCHEMBL3386031 0.79 POLB (0.41) PDK2HSD11B1ALDH1A1L3MBTL1POLB
SCHEMBL29369047 0.79 POLB (0.41) PDK2HSD11B1ALDH1A1L3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117645771-A Solvent-free high-low temperature resistant bulletproof composite matrix resin and preparation method thereof 上海鑫丰泰新材料科技有限公司 2024-03-05 CN claimed
CN-115975192-A Polyimide slurry, polyimide film, and preparation method and application thereof 江西沃格光电股份有限公司 2023-04-18 CN claimed
CN-114939226-B Pancreatin inactivation stent drainage tube applied to pancreaticojejunostomy and preparation method thereof 中南大学 2022-11-25 CN claimed
CN-115160566-A Polyimide, slurry, film, preparation method of polyimide, slurry, film and flexible display device 江西沃格光电股份有限公司 2022-10-11 CN claimed
CN-114939226-A Pancreatin inactivation stent drainage tube applied to pancreaticojejunostomy and preparation method thereof 中南大学 2022-08-26 CN claimed
CN-114874623-A Polyimide resin slurry, polyimide conduit, and preparation method and application thereof 中国科学院化学研究所 2022-08-09 CN claimed
CN-110951099-B Polyimide film, preparation method thereof and base film of radio frequency flexible printed circuit 中天电子材料有限公司 2020-09-25 CN claimed
CN-107722272-B Preparation method of polyimide film 湖北鼎龙控股股份有限公司 2020-07-14 CN claimed
CN-110951099-A Polyimide film, preparation method thereof and base film of radio frequency flexible printed circuit 中天电子材料有限公司 2020-04-03 CN claimed
CN-117645771-A Solvent-free high-low temperature resistant bulletproof composite matrix resin and preparation method thereof 上海鑫丰泰新材料科技有限公司 2024-03-05 CN disclosed
CN-111533909-B Polyamide imide, polyamide imide film and display device 武汉柔显科技股份有限公司 2023-04-25 CN disclosed
CN-115975192-A Polyimide slurry, polyimide film, and preparation method and application thereof 江西沃格光电股份有限公司 2023-04-18 CN disclosed
CN-115160566-A Polyimide, slurry, film, preparation method of polyimide, slurry, film and flexible display device 江西沃格光电股份有限公司 2022-10-11 CN disclosed
CN-114874623-A Polyimide resin slurry, polyimide conduit, and preparation method and application thereof 中国科学院化学研究所 2022-08-09 CN disclosed
CN-107652433-B Preparation method of polyimide 湖北鼎龙控股股份有限公司 2020-07-07 CN disclosed
CN-110951099-A Polyimide film, preparation method thereof and base film of radio frequency flexible printed circuit 中天电子材料有限公司 2020-04-03 CN disclosed
CN-110790929-A Colorless transparent high-modulus polyimide film and preparation method thereof 上海金門量子科技有限公司 2020-02-14 CN disclosed
CN-110628025-A Polyimide precursor, polyimide, and material for use in preparation thereof 宇部兴产株式会社 2019-12-31 CN disclosed
EP-2061776-A1 ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE Wyeth a Corporation of the State of Delaware (US) 2009-05-27 EP disclosed
WO-2008073459-A1 ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE WYETH (US) 2008-06-19 WO disclosed