Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4392002 | 0.85 | PDK2 (0.42) | ALDH1A1L3MBTL1HSD11B1NOTUMPOLB | |
| SCHEMBL197671 | 0.85 | HSD11B1 (0.56) | ALDH1A1L3MBTL1HSD11B1NOTUMPOLB | |
| SCHEMBL3789801 | 0.85 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1HSD11B1NOTUMPOLB | |
| SCHEMBL8022901 | 0.83 | HSD11B1 (0.54) | ALDH1A1L3MBTL1HSD11B1NOTUMPOLB | |
| Hydrochloric Acid SCHEMBL29010139 | 0.83 | HSD11B1 (0.54) | ALDH1A1L3MBTL1HSD11B1NOTUMPOLB | |
| SCHEMBL3787576 | 0.82 | TSHR (0.52) | ALDH1A1L3MBTL1HSD11B1NOTUMPOLB | |
| SCHEMBL29518515 | 0.82 | BACE1 (0.49) | ALDH1A1L3MBTL1HSD11B1POLBGLA | |
| SCHEMBL2478064 | 0.82 | TSHR (0.57) | ALDH1A1L3MBTL1HSD11B1POLBGLA | |
| SCHEMBL693143 | 0.82 | TSHR (0.62) | ALDH1A1HSD11B1NOTUMPOLBGLA | |
| SCHEMBL3790634 | 0.82 | TSHR (0.74) | ALDH1A1L3MBTL1HSD11B1POLBGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104558607-A | Polyimide resin capable of being cured at low temperature and preparation method thereof | LG CHEMICAL LTD | 2015-04-29 | — | — | CN | claimed |
| CN-102364397-B | Radiation-sensitive resin composition, cured film, method for forming cured film, and display device | JSR CORP | 2015-04-01 | — | — | CN | claimed |
| CN-1168765-C | High-temperature resistant rigid-rod-shaped clay organic intercalation agent and preparation method thereof | 上海交通大学 | 2004-09-29 | — | — | CN | claimed |
| CN-1379057-A | High-temperature resistant rigid-rod-shaped clay organic intercalation agent and preparation method thereof | UNIV SHANGHAI JIAOTONG (CN) | 2002-11-13 | — | — | CN | claimed |
| EP-3256461-B1 | UREA AND SULFONAMIDE DERIVATIVES AS HUMAN HELICASE DDX3 INHIBITORS USEFUL IN THE TREATMENT OF VIRAL DISEASES | AZIENDA OSPEDALIERA UNIV SENESE (IT) | 2023-09-13 | — | — | EP | disclosed |
| CN-115232471-A | Polyimide film and electronic device | 杜邦电子公司 | 2022-10-25 | — | — | CN | disclosed |
| EP-3432881-B1 | USE OF DDX3 INHIBITORS AS ANTIPROLIFERATIVE AGENTS | AZIENDA OSPEDALIERA UNIV SENESE (IT) | 2021-11-24 | — | — | EP | disclosed |
| CN-113613904-A | Polyamic acid composition and method for producing same, polyamic acid solution, polyimide film, laminate and method for producing same, and flexible device and method for producing same | 株式会社钟化 | 2021-11-05 | — | — | CN | disclosed |
| US-11000512-B2 | Use of DDX3 inhibitors as antiproliferative agents | AZIENDA OSPEDALIERA UNIVERSITARIA SENESE (IT) | 2021-05-11 | — | — | US | disclosed |
| US-10941121-B2 | Human helicase DDX3 inhibitors as therapeutic agents | AZIENDA OSPEDALIERA UNIVERSITARIA SENESE (IT) | 2021-03-09 | — | — | US | disclosed |
| EP-3705477-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | Vertex Pharmaceuticals Incorporated (US) | 2020-09-09 | — | — | EP | disclosed |
| US-10662192-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2020-05-26 | — | — | US | disclosed |
| CN-1168765-C | High-temperature resistant rigid-rod-shaped clay organic intercalation agent and preparation method thereof | 上海交通大学 | 2004-09-29 | — | — | CN | disclosed |
| CN-1471659-A | Positive photosensitive resin precursor and process for producing the same | 东丽株式会社 | 2004-01-28 | — | — | CN | disclosed |
| CN-1457454-A | Precursor composition for positive photosensitive resin and display made with the same | TORAY INDUSTRIES (JP) | 2003-11-19 | — | — | CN | disclosed |
| CN-1379057-A | High-temperature resistant rigid-rod-shaped clay organic intercalation agent and preparation method thereof | UNIV SHANGHAI JIAOTONG (CN) | 2002-11-13 | — | — | CN | disclosed |
| EP-1175406-A1 | IMIDAZOLINE DERIVATIVES AS ALPHA-1A ADRENOCEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000066563-A1 | IMIDAZOLINE DERIVATIVES AS ALPHA-1A ADRENOCEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2000-11-09 | — | — | WO | disclosed |
| CN-1211743-A | Multi-domain STN LCD comprising fluorinated polyimide alignment layers | MERCK PATENT GMBH (DE) | 1999-03-24 | — | — | CN | disclosed |
| CN-1072562-A | HERBICIDAL BIPHENYLAMINE DERIVATIVES | DU PONT (US) | 1993-06-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11000512-B2 | Use of DDX3 inhibitors as antiproliferative agents | DDX3X, DDX21, DDB1 | ALDH1A1 2284/4885L3MBTL1 1706/4885HSD11B1 1174/4885 |
| US-10662192-B2 | Modulators of ATP-binding cassette transporters | CFTR, ABCB1, ABCC2 | ALDH1A1 2165/4885L3MBTL1 3552/4885HSD11B1 2076/4885 |
| US-10941121-B2 | Human helicase DDX3 inhibitors as therapeutic agents | DDX3X, DDX39B, DDX1 | ALDH1A1 2606/4885L3MBTL1 669/4885HSD11B1 1455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.