Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | ERN1 | O75460 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28765646 | 0.87 | L3MBTL1 (0.71) | MAPTNPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL12290142 | 0.86 | MAPT (0.71) | MAPTNPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL29844427 | 0.83 | L3MBTL1 (0.75) | MAPTNPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL10783231 | 0.83 | MAPT (0.68) | MAPTNPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL1253291 | 0.83 | L3MBTL1 (0.75) | MAPTNPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL24682276 | 0.83 | L3MBTL1 (0.70) | MAPTNPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL31573999 | 0.83 | MAPT (0.68) | MAPTNPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL2560912 | 0.83 | L3MBTL1 (0.67) | MAPTNPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL2560084 | 0.81 | MAPT (0.61) | MAPTNPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL2998966 | 0.81 | L3MBTL1 (0.86) | MAPTNPC1RAB9AL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090304620-A1 | HAIR TREATMENT PRODUCTS COMPRISING POLYMERS | HENKEL AG & CO. KGAA (DE) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090304620-A1 | HAIR TREATMENT PRODUCTS COMPRISING POLYMERS | ASS1, SRM, COL1A1 | MAPT 1499/4885NPC1 4811/4885RAB9A 4866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.