SCHEMBL439228

SCHEMBL439228

Cc1ccc(-c2ccccc2N=C=Nc2ccccc2-c2ccc(C)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
POLB P06746 2/20 0.36
RAB9A P51151 7/20 0.35
NPC1 O15118 6/20 0.35
SYK P43405 1/20 0.35
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
GAA P10253 1/20 0.34
LMNA P02545 3/20 0.34
HPGD P15428 3/20 0.34
KDM4E B2RXH2 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
NR2F2 P24468 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7585382 0.85 CYP3A4 (0.52) CASP3SENP8SENP7SENP6MEN1
SCHEMBL6269790 0.81 RAB9A (0.42) CASP3SENP8SENP7SENP6MEN1
SCHEMBL13674376 0.78 KMT2A (0.41) CASP3SENP8SENP7SENP6MEN1
SCHEMBL8036362 0.75 LMNA (0.50) MEN1KMT2APOLBRAB9ANPC1
SCHEMBL28894180 0.73 CASP3 (0.35) CASP3SENP8SENP7SENP6MEN1
SCHEMBL287022 0.72 TSHR (0.43) MEN1KMT2APOLBRAB9ANPC1
SCHEMBL3294988 0.71 LMNA (0.53) MEN1KMT2APOLBRAB9ANPC1
SCHEMBL29688196 0.71 LMNA (0.53) MEN1KMT2APOLBRAB9ANPC1
SCHEMBL692232 0.71 CYP3A4 (0.44) CASP3SENP8SENP7SENP6ALDH1A1
SCHEMBL29770893 0.71 CYP3A4 (0.44) CASP3SENP8SENP7SENP6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8247156-B2 Processes for producing polyester latexes with improved hydrolytic stability XEROX CORPORATION (US) 2012-08-21 US claimed
US-20120064453-A1 PROCESSES FOR PRODUCING POLYESTER LATEXES WITH IMPROVED HYDROLYTIC STABILITY XEROX CORPORATION (US) 2012-03-15 US claimed
EP-1000103-B1 AQUEOUS SULFOPOLYUREA COLLOIDAL DISPERSIONS MINNESOTA MINING & MFG (US) 2002-10-23 EP claimed
US-6165239-A Aqueous sulfopolyurea colloidal dispersions, films and abrasive articles 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-12-26 US claimed
EP-1000103-A1 AQUEOUS SULFOPOLYUREA COLLOIDAL DISPERSIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-05-17 EP claimed
WO-1999005192-A1 AQUEOUS SULFOPOLYUREA COLLOIDAL DISPERSIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-02-04 WO claimed
US-9719011-B2 Proppant BASF SE (DE) 2017-08-01 US disclosed
US-9714378-B2 Proppant BASF SE (DE) 2017-07-25 US disclosed
EP-2705009-B1 AN ENCAPSULATED PARTICLE BASF SE (DE) 2017-03-08 EP disclosed
EP-2705010-B1 A DUST SUPPRESSING AGGREGATE BASF SE (DE) 2016-12-07 EP disclosed
US-9353020-B2 Dust suppressing aggregate BASF SE (DE) 2016-05-31 US disclosed
US-20150315458-A1 A Proppant BASF SE (DE) 2015-11-05 US disclosed
EP-2931831-A1 A PROPPANT BASF SE (DE) 2015-10-21 EP disclosed
EP-2350228-A1 A PROPPANT BASF SE (DE) 2011-08-03 EP disclosed
WO-2010049467-A1 A PROPPANT BASF SE (DE) 2010-05-06 WO disclosed
EP-1000103-B1 AQUEOUS SULFOPOLYUREA COLLOIDAL DISPERSIONS MINNESOTA MINING & MFG (US) 2002-10-23 EP disclosed
US-6165239-A Aqueous sulfopolyurea colloidal dispersions, films and abrasive articles 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-12-26 US disclosed
EP-1000103-A1 AQUEOUS SULFOPOLYUREA COLLOIDAL DISPERSIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-05-17 EP disclosed
WO-1999005192-A1 AQUEOUS SULFOPOLYUREA COLLOIDAL DISPERSIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-02-04 WO disclosed
US-4113676-A Aqueous dispersions of esters stabilized with carbodiimides PPG INDUSTRIES, INC. (US) 1978-09-12 US disclosed