SCHEMBL4392802

SCHEMBL4392802

Nc1cccc(S(=O)(=O)CCCl)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.57
CA2 P00918 4/20 0.55
CA12 O43570 3/20 0.55
CA1 P00915 3/20 0.55
CA9 Q16790 3/20 0.55
CA4 P22748 2/20 0.55
CA14 Q9ULX7 1/20 0.55
ALDH1A1 P00352 2/20 0.53
TSHR P16473 1/20 0.53
HSD17B10 Q99714 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
CYP19A1 P11511 1/20 0.46
F2 P00734 3/20 0.46
PRSS1 P07477 3/20 0.46
PRSS2 P07478 3/20 0.46
PRSS3 P35030 3/20 0.46
POLB P06746 2/20 0.45
PRMT1 Q99873 1/20 0.43
PKM P14618 2/20 0.41
HTR6 P50406 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL55285 0.86 CA1 (0.44) LMNACA2CA12CA1CA9
SCHEMBL3024800 0.81 LMNA (0.57) LMNACA2CA12CA1CA9
SCHEMBL29656296 0.81 ALDH1A1 (0.58) LMNACA2CA12CA1CA9
SCHEMBL922778 0.81 ALDH1A1 (0.58) LMNACA2CA12CA1CA9
Hydrochloric Acid SCHEMBL1144014 0.80 ALDH1A1 (0.56) LMNACA2CA12CA1CA9
SCHEMBL1965280 0.80 ALDH1A1 (0.61) LMNACA2CA12CA1CA9
SCHEMBL11339427 0.79 CA2 (0.56) LMNACA2CA12CA1CA9
SCHEMBL11329245 0.79 CA2 (0.56) LMNACA2CA12CA1CA9
SCHEMBL1156252 0.79 LMNA (0.63) LMNACA2CA12CA1CA9
SCHEMBL29737578 0.79 LMNA (0.63) LMNACA2CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1411090-B1 Monoazo reactive red dyestuff EVERLIGHT USA INC (US) 2009-11-25 EP disclosed
CN-1257233-C Monoazo Reactive Red Dye EVERLIGHT CHEM IND CORP (CN) 2006-05-24 CN disclosed
US-6815536-B2 DYESTUFFS FOR DYEING AND PRINTING OF MATERIALS CONTAINING EITHER CELLULOSE FIBERS, SUCH AS COTTON, ARTIFICIAL COTTON, LINEN, AND ARTIFICIAL LINEN, OR SYNTHETIC POLYAMIDE, SUCH AS WOOL, SILK, AND NYLON ETC. EVERLIGHT USA, INC. 2004-11-09 US disclosed
US-20040087780-A1 Monoazo reactive red dyestuff EVERLIGHT USA, INC. 2004-05-06 US disclosed
CN-1493623-A Monoazo Reactive Red Dye 台湾永光化学工业股份有限公司 2004-05-05 CN disclosed
EP-1411090-A1 Monoazo reactive red dyestuff Everlight USA, Inc. (US) 2004-04-21 EP disclosed
EP-0841323-B1 Method for producing arylvinylsulfone SUMITOMO CHEMICAL CO (JP) 2003-03-05 EP disclosed
US-6407220-B1 FOR DYEING AND PRINTING OF MATERIALS CONTAINING CELLULOSE FIBERS; HIGH FIXATION AND GOOD BUILD-UP EVERLIGHT USA, INC. 2002-06-18 US disclosed
US-6015885-A COLOR-STABLE, WATERPROOF DYES FOR NATURAL FIBERS OR REGENERATED CELLULOSE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-01-18 US disclosed
US-5902905-A Method for producing arylvinylsulfone SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-05-11 US disclosed
US-4607102-A CELLULOSE FIBERS, COLORFSTNESS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-08-19 US disclosed
EP-0167219-A1 Fiber-reactive compound having both pyridiniotriazinyl and vinylsulfone type groups SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-01-08 EP disclosed
US-4505714-A Phthalocyanine fiber reactive compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-03-19 US disclosed
EP-0071035-B1 REACTIVE MONO-FUNCTIONAL BISAZO BLUE-BLACK DYE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-11-07 EP disclosed
US-4464297-A Fiber reactive bisazo dye having both a vinylsulfone type reactive group and an ortho-nitrophenyl group SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-08-07 US disclosed
EP-0042108-B1 REACTIVE DYES, THEIR USE AND CELLULOSE FIBERS DYED THEREWITH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-04-04 EP disclosed
EP-0099721-A1 Reactive metal formazan blue dye SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-02-01 EP disclosed
EP-0071035-A1 Reactive mono-functional bisazo blue-black dye SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-02-09 EP disclosed
EP-0042108-A1 Reactive dyes, their use and cellulose fibers dyed therewith SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-12-23 EP disclosed
US-4035350-A Process for the preparation of water-soluble azo dyestuffs by reacting an aromatic amine and a coupling component with alkali metal nitrite or alkyl nitrite in the absence of acid HOECHST AKTIENGESELLSCHAFT (DT) 1977-07-12 US disclosed