Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 6/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 3/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | PKLR | P30613 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29656296 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| Hydrochloric Acid SCHEMBL1144014 | 0.98 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| Phosphoric Acid SCHEMBL11704340 | 0.93 | ALDH1A1 (0.51) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| Sulfanilamide SCHEMBL8472428 | 0.89 | CA2 (0.63) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| SCHEMBL10778942 | 0.85 | ALDH1A1 (0.62) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| SCHEMBL13989387 | 0.84 | ALDH1A1 (0.49) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| SCHEMBL1965280 | 0.84 | ALDH1A1 (0.61) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| L-Phenylalaninol SCHEMBL8201376 | 0.83 | PRMT1 (0.44) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| SCHEMBL10603340 | 0.82 | POLB (0.62) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| SCHEMBL4392802 | 0.81 | LMNA (0.57) | ALDH1A1TSHRHSD17B10TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100166765-A1 | BENZOQUINAZOLINE DERIVATIVES | NOVARTIS AG (CH) | 2010-07-01 | — | — | US | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1761541-B1 | PYRRAZOLO-PYRIMIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-01-09 | — | — | EP | claimed |
| EP-1761541-A1 | PYRRAZOLO-PYRIMIDINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2007-03-14 | — | — | EP | claimed |
| WO-2005123738-A1 | PYRRAZOLO-PYRIMIDINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2005-12-29 | — | — | WO | claimed |
| US-6172261-B1 | BIOSYNTHESIS USING CHAIN EXTENSION | ORIDIGM CORPORATION | 2001-01-09 | — | — | US | claimed |
| CN-1030984-C | Method for preparing amino aryl-beta-sulfatoethyl sulfone | HOECHST AG (DE) | 1996-02-14 | — | — | CN | claimed |
| US-5463100-A | Spraying a mixture of an aminoaryl beta-hydroxyethylsulfone and sulfuric acid into a hot gas stream; drying, esterification and any hydrolysis take place simultaneously; granules | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | claimed |
| EP-0390826-B1 | PROCESS FOR PRODUCING AMINOARYL-BETA-SULPHATOETHYLSULPHONE COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-19 | — | — | EP | claimed |
| CN-1033867-A | CIGARETTE LIGHTER | TDK CORP (JP) | 1989-07-12 | — | — | CN | claimed |
| US-4450114-A | Process for production of sulfuric acid semiesters | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-05-22 | — | — | US | claimed |
| US-4372892-A | Process for the preparation of 1-aminobenzene-5-β-sulfatoethylsulfone-2,4-disulfonic acid, the 5-vinylsulfone compound and the alkali salts thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-08 | — | — | US | claimed |
| JP-3038562-A | — | — | None | — | — | JP | disclosed |
| JP-63039854-A | — | — | None | — | — | JP | disclosed |
| CN-114921113-B | Green and environment-friendly production process of active anthraquinone turquoise blue dye | 浙江亿得新材料股份有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-114014912-B | Method for preparing leuprorelin by combining solid phase and liquid phase | 浙江湃肽生物有限公司南京分公司 | 2022-03-29 | — | — | CN | disclosed |
| US-4066638-A | WATER-SOLUBLE FIBER REACTIVE PHENYL-AZO-NAPHTHYL DYESTUFFS CONTAINING TWO SULFO GROUPS IN THE PHENYL MOIETY | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-01-03 | — | — | US | disclosed |
| US-4033980-A | Phthalocyanine dyestuffs and process for preparing them | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-07-05 | — | — | US | disclosed |
| US-4002606-A | FIBER-REACTIVE DYES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-01-11 | — | — | US | disclosed |
| US-3980677-A | Anthraquinone dyestuffs containing sulphonic acid groups | BAYER AKTIENGESELLSCHAFT (DT) | 1976-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100166765-A1 | BENZOQUINAZOLINE DERIVATIVES | CACNA1A, BMP4, TPX2 | ALDH1A1 3966/4885TSHR 2266/4885HSD17B10 4016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.