Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.48 |
| ▸ | CHRNA1 | P02708 | 4/20 | 0.48 |
| ▸ | CHRNG | P07510 | 4/20 | 0.48 |
| ▸ | CHRNB1 | P11230 | 4/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.48 |
| ▸ | CHRND | Q07001 | 4/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.48 |
| ▸ | OGG1 | O15527 | 1/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL770168 | 0.83 | SLC6A3 (0.65) | CYP2B6SLC6A3SLC6A2CHRNA1CHRNG | |
| SCHEMBL16992600 | 0.74 | HTR1B (0.49) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL20481912 | 0.74 | HTR1B (0.49) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL4399949 | 0.74 | CYP2B6 (0.57) | CYP2B6SLC6A3SLC6A2CHRNA1CHRNG | |
| SCHEMBL2955630 | 0.74 | CYP2B6 (1.00) | CYP2B6SLC6A3SLC6A2CHRNA1CHRNG | |
| SCHEMBL29486913 | 0.74 | CYP2B6 (1.00) | CYP2B6SLC6A3SLC6A2CHRNA1CHRNG | |
| SCHEMBL2955633 | 0.74 | CYP2B6 (1.00) | CYP2B6SLC6A3SLC6A2CHRNA1CHRNG | |
| SCHEMBL1226857 | 0.74 | CYP2B6 (1.00) | CYP2B6SLC6A3SLC6A2CHRNA1CHRNG | |
| SCHEMBL4240834 | 0.73 | OGG1 (0.53) | OGG1ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10656522 | 0.72 | CYP2B6 (0.51) | CYP2B6SLC6A3SLC6A2CHRNA1CHRNG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188150-B2 | Use of beta-aminoalcohols in the treatment of inflammatory disorders and pain | BIOCOPEA LIMITED (GB) | 2012-05-29 | — | — | US | disclosed |
| US-20090306216-A1 | Use of Beta-Aminoalcohols in the Treatment of Inflammatory Disorders and Pain | BIOCOPEA LIMITED (GB) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306216-A1 | Use of Beta-Aminoalcohols in the Treatment of Inflammatory Disorders and Pain | OPRL1, HRH3, NR1H2 | CYP2B6 1336/4885SLC6A3 2825/4885SLC6A2 1357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.