Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.49 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CTSK | P43235 | 5/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL4393420 | 1.00 | ANPEP (0.49) | ANPEPRNPEPDNPEPALDH1A1CTSK | |
| SCHEMBL353695 | 0.95 | ALDH1A1 (0.53) | ANPEPRNPEPDNPEPALDH1A1CTSK | |
| SCHEMBL355730 | 0.95 | ALDH1A1 (0.53) | ANPEPRNPEPDNPEPALDH1A1CTSK | |
| SCHEMBL728728 | 0.95 | ALDH1A1 (0.53) | ANPEPRNPEPDNPEPALDH1A1CTSK | |
| Hydrochloric Acid SCHEMBL1810902 | 0.94 | ALDH1A1 (0.51) | ANPEPRNPEPDNPEPALDH1A1CTSK | |
| Hydrochloric Acid SCHEMBL7365467 | 0.94 | ALDH1A1 (0.51) | ANPEPRNPEPDNPEPALDH1A1CTSK | |
| Hydrochloric Acid SCHEMBL9697973 | 0.94 | ALDH1A1 (0.51) | ANPEPRNPEPDNPEPALDH1A1CTSK | |
| Alcohol SCHEMBL28297582 | 0.90 | ANPEP (0.48) | ANPEPRNPEPDNPEPALDH1A1CTSK | |
| Toluene SCHEMBL27746059 | 0.90 | ANPEP (0.48) | ANPEPRNPEPDNPEPALDH1A1CTSK | |
| Phenylalanine SCHEMBL11683484 | 0.87 | SLC7A5 (0.61) | ANPEPRNPEPDNPEPALDH1A1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981544-B1 | BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE) HYDROGEL, PREPARATION METHOD THEREOF AND USE THEREOF | KIST KOREA INSTITUTE OF SCIENCE AND TECH (KR) | 2019-06-19 | — | — | EP | disclosed |
| US-9526699-B2 | Biodegradable and thermosensitive poly(organophosphazene) hydrogel, preparation method thereof and use thereof | KIST (KR) | 2016-12-27 | — | — | US | disclosed |
| CN-101360513-B | Biodegradable and thermosensitive poly(organophosphazene) hydrogel, preparation method thereof and use thereof | KOREA INST SCI & TECH | 2013-01-23 | — | — | CN | disclosed |
| CN-101360513-A | Biodegradable and thermosensitive poly(organophosphazene) hydrogel, preparation method thereof and use thereof | KOREA INST SCI & TECH (KR) | 2009-02-04 | — | — | CN | disclosed |
| US-20090022683-A1 | Biodegradable and Thermosensitive Poly(Organophosphazene) Hydrogel, Preparation Method Thereof and Use Thereof | KIST (KR) | 2009-01-22 | — | — | US | disclosed |
| EP-1981544-A2 | BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE) HYDROGEL, PREPARATION METHOD THEREOF AND USE THEREOF | KIST Korea Institute of Science and Technology (KR) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007083875-A2 | BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE) HYDROGEL, PREPARATION METHOD THEREOF AND USE THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2007-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090022683-A1 | Biodegradable and Thermosensitive Poly(Organophosphazene) Hydrogel, Preparation Method Thereof and Use Thereof | PHOSPHO1, PGLS, LIPE | ANPEP 1568/4885RNPEP 1823/4885DNPEP 1491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.