SCHEMBL728728

SCHEMBL728728

CC(C)CC(N)C(=O)OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
ANPEP P15144 1/20 0.52
RNPEP Q9H4A4 1/20 0.52
DNPEP Q9ULA0 1/20 0.52
CTSK P43235 4/20 0.51
CTSB P07858 2/20 0.50
CTSS P25774 2/20 0.48
CTSL P07711 1/20 0.48
IDO1 P14902 1/20 0.48
SLC15A1 P46059 1/20 0.48
SLC1A1 P43005 1/20 0.48
MAPK1 P28482 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A3 Q01959 1/20 0.47
KMT2A Q03164 1/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL355730 1.00 ALDH1A1 (0.53) ALDH1A1ANPEPRNPEPDNPEPCTSK
SCHEMBL353695 1.00 ALDH1A1 (0.53) ALDH1A1ANPEPRNPEPDNPEPCTSK
Hydrochloric Acid SCHEMBL7365467 0.98 ALDH1A1 (0.51) ALDH1A1ANPEPRNPEPDNPEPCTSK
Hydrochloric Acid SCHEMBL1810902 0.98 ALDH1A1 (0.51) ALDH1A1ANPEPRNPEPDNPEPCTSK
Hydrochloric Acid SCHEMBL9697973 0.98 ALDH1A1 (0.51) ALDH1A1ANPEPRNPEPDNPEPCTSK
Oxalic Acid SCHEMBL4393417 0.95 ANPEP (0.49) ALDH1A1ANPEPRNPEPDNPEPCTSK
Oxalic Acid SCHEMBL4393420 0.95 ANPEP (0.49) ALDH1A1ANPEPRNPEPDNPEPCTSK
Toluene SCHEMBL27746059 0.94 ANPEP (0.48) ALDH1A1ANPEPRNPEPDNPEPCTSK
Alcohol SCHEMBL28297582 0.94 ANPEP (0.48) ALDH1A1ANPEPRNPEPDNPEPCTSK
Phenylalanine SCHEMBL11683484 0.91 SLC7A5 (0.61) ALDH1A1ANPEPRNPEPDNPEPCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192379-A Marine cyclic peptide and synthesis method and application thereof 内蒙古大学 2025-06-24 CN claimed
CN-102320950-B Method for synthesizing acetic acid through carbonylation SHANGHAI HUAYI GROUP CO 2015-05-13 CN claimed
CN-102250202-B 1-paranitrophenyl-beta-carboline-3-formyl amine acid carbamates and synthesis method and use thereof UNIV CAPITAL MEDICAL SCIENCES 2013-08-28 CN claimed
CN-101659607-B Method for preparing acetic acid and acetic anhydride respectively or synchronously SHANGHAI COKING & CHEM CORP 2013-04-10 CN claimed
CN-101927201-B Method for removing impurities from solution of acetic acid and/or acetic anhydride hydroformylation catalyst SHANGHAI COKING & CHEM CORP 2012-12-12 CN claimed
CN-102241674-B Synthesis method and antitumor activity evaluation of 1,1-dimethyl-beta-carboline-3-formacyl amino acid benzyl ester UNIV CAPITAL MEDICAL 2012-09-12 CN claimed
CN-101906102-B Beta-carboline alkaloid derivative, preparation method and application thereof UNIV CAPITAL MEDICAL 2012-08-29 CN claimed
CN-102320950-A Method for synthesizing acetic acid through carbonylation SHANGHAI HUAYI GROUP CO 2012-01-18 CN claimed
CN-102250202-A 1-paranitrophenyl-beta-carboline-3-formyl amine acid carbamates and synthesis method and use thereof UNIV CAPITAL MEDICAL 2011-11-23 CN claimed
CN-102241674-A Synthesis method and antitumor activity evaluation of 1,1-dimethyl-beta-carboline-3-formacyl amino acid benzyl ester UNIV CAPITAL MEDICAL 2011-11-16 CN claimed
CN-101658800-B Catalyst system for use in preparation of acetic acid and acetic anhydride or synchronous preparation of acetic acid and acetic anhydride and preparation method thereof SHANGHAI COKING & CHEM CORP 2011-11-02 CN claimed
CN-101927201-A Method for removing impurities from solution of acetic acid and/or acetic anhydride hydroformylation catalyst SHANGHAI COKING & CHEM CORP 2010-12-29 CN claimed
CN-101497615-B Substituted purine, preparation and use in medicine ZHEJIANG MED XINCHANG PHARM 2010-12-15 CN claimed
CN-101906102-A Beta-carboline alkaloid derivative, preparation method and application thereof UNIV CAPITAL MEDICAL 2010-12-08 CN claimed
CN-101658800-A Catalyst system for use in preparation of acetic acid and acetic anhydride or synchronous preparation of acetic acid and acetic anhydride and preparation method thereof SHANGHAI COKING & CHEMICAL COR 2010-03-03 CN claimed
CN-101659607-A Method for preparing acetic acid and acetic anhydride respectively or synchronously SHANGHAI COKING & CHEMICAL COR 2010-03-03 CN claimed
CN-101597290-A β-Ka Lin-3-formyl tryptophyl amino-acid benzyl ester and its production and application UNIV CAPITAL MEDICAL (CN) 2009-12-09 CN claimed
CN-101597289-A 2-tryptophyl-beta-tetrahydro carboline-3-formyol amino-acid benzyl ester and its production and application UNIV CAPITAL MEDICAL (CN) 2009-12-09 CN claimed
CN-101497615-A Substituted purine, preparation and use in medicine XINCHANG PHARMACEUTICAL FACTORY ZHEJIANG MEDICINE CO LTD (CN) 2009-08-05 CN claimed
EP-3364958-B1 MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF NAVITOR PHARM INC (US) 2023-01-04 EP disclosed
EP-4112611-A2 MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF Navitor Pharmaceuticals, Inc. (US) 2023-01-04 EP disclosed
US-11040939-B1 N-transfer reagent and method for preparing the same and its application NATIONAL CHENG KUNG UNIVERSITY (TW) 2021-06-22 US disclosed
CN-111909979-A Preparation method of L-glufosinate-ammonium 武汉英凯生物技术研究院有限公司 2020-11-10 CN disclosed
CN-111748589-A Preparation method of L-glufosinate-ammonium 武汉茵茂特生物技术有限公司 2020-10-09 CN disclosed
CN-106317169-B Double indoles-dipeptidase derivants, synthesis, antithrombotic acitivity and the application for preparing antithrombotic agents 首都医科大学 2019-07-02 CN disclosed
CN-108948138-A A kind of preparation method of leucine dipeptide 南京纽邦生物科技有限公司 2018-12-07 CN disclosed
CN-107501451-A Chiral CO2Respond ethyleneamino acid polymer and preparation method thereof 北方民族大学 2017-12-22 CN disclosed
US-9822146-B2 Process for the manufacture of degarelix and its intermediates FERRING B.V. (NL) 2017-11-21 US disclosed
WO-2017070518-A1 MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF NAVITOR PHARMACEUTICALS, INC. (US) 2017-04-27 WO disclosed
CN-106349148-A Novel indoles compound having anti-tumor metastasis activity and anti-inflammatory activity, as well as synthesis and application of novel indoles compound 首都医科大学 2017-01-25 CN disclosed
CN-104447394-B Novel synthesis process of ubenimex 成都傲飞生物化学品有限责任公司 2017-01-18 CN disclosed
CN-106317169-A Bisindole-dipeptide derivatives, synthesis and antithrombotic activity thereof, and application of derivatives in preparation of antithrombotic agents 首都医科大学 2017-01-11 CN disclosed
EP-2632935-B1 PROCESS FOR THE MANUFACTURE OF DEGARELIX AND ITS INTERMEDIATES FERRING BV (NL) 2016-09-21 EP disclosed
US-20160145301-A1 PROCESS FOR THE MANUFACTURE OF DEGARELIX AND ITS INTERMEDIATES FERRING BV (NL) 2016-05-26 US disclosed
US-9175006-B2 Compositions and methods for cyclofructans as separation agents BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2015-11-03 US disclosed
US-9175006-B2 Compositions and methods for cyclofructans as separation agents BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2015-11-03 US disclosed
US-9175006-B2 Compositions and methods for cyclofructans as separation agents BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2015-11-03 US disclosed
US-9090656-B2 Process for the manufacture of Degarelix and its intermediates FERRING B.V. (NL) 2015-07-28 US disclosed
CN-103450197-B Cyclohexyl tetrahydro imidazo pyrido indole-diketone acetyl amino acids, and synthesis, antithrombotic effect and application thereof UNIV CAPITAL MEDICAL SCIENCES 2015-07-08 CN disclosed
CN-102320950-B Method for synthesizing acetic acid through carbonylation SHANGHAI HUAYI GROUP CO 2015-05-13 CN disclosed
US-20140051706-A1 ALPHA HELIX MIMETICS AND METHODS RELATING THERETO PRISM PHARMA CO., LTD. (JP) 2014-02-20 US disclosed
CN-103517904-A Alpha-helix mimetics and methods relating thereto PRISM BIOLAB CORP 2014-01-15 CN disclosed
EP-2678341-A1 ALPHA HELIX MIMETICS AND METHODS RELATING THERETO PRISM Pharma Co., Ltd. (JP) 2014-01-01 EP disclosed
CN-103450197-A Cyclohexyl tetrahydro imidazo pyrido indole-diketone acetyl amino acids, and synthesis, antithrombotic effect and application thereof UNIV CAPITAL MEDICAL SCIENCES 2013-12-18 CN disclosed
CN-103435688-A Novel method for preparing compound of natural glycosyl-1-phosphoryl dipeptide and phosphoramide UNIV JIANGXI NORMAL SCI & TECH 2013-12-11 CN disclosed
US-20130281661-A1 PROCESS FOR THE MANUFACTURE OF DEGARELIX AND ITS INTERMEDIATES FERRING B.V. (NL) 2013-10-24 US disclosed
EP-1619189-B1 N-(3-acyl-2-hydroxyalkyl) cycloalkyl amide derivatives SEIKAGAKU KOGYO CO LTD (JP) 2013-09-04 EP disclosed
EP-2632935-A1 PROCESS FOR THE MANUFACTURE OF DEGARELIX AND ITS INTERMEDIATES Ferring B.V. (NL) 2013-09-04 EP disclosed
CN-102250202-B 1-paranitrophenyl-beta-carboline-3-formyl amine acid carbamates and synthesis method and use thereof UNIV CAPITAL MEDICAL SCIENCES 2013-08-28 CN disclosed
CN-102329376-B Cyclo(phenylalanine-N-methylleucyl-leucyl-N-methylleucyl-leucyl), and synthesis method and application thereof UNIV JINAN 2013-07-10 CN disclosed
CN-101090902-B Cgrp receptor antagonists MERCK SHARP & DOHME 2013-05-29 CN disclosed
CN-101659607-B Method for preparing acetic acid and acetic anhydride respectively or synchronously SHANGHAI COKING & CHEM CORP 2013-04-10 CN disclosed
CN-101927201-B Method for removing impurities from solution of acetic acid and/or acetic anhydride hydroformylation catalyst SHANGHAI COKING & CHEM CORP 2012-12-12 CN disclosed
US-20120231972-A1 Probe Compound for Detecting and Isolating Enzymes and Means and Methods Using the Same INSTITUTE OF CATALYSIS (CSIC) (ES) 2012-09-13 US disclosed
CN-102241674-B Synthesis method and antitumor activity evaluation of 1,1-dimethyl-beta-carboline-3-formacyl amino acid benzyl ester UNIV CAPITAL MEDICAL 2012-09-12 CN disclosed
WO-2012115286-A1 ALPHA HELIX MIMETICS AND METHODS RELATING THERETO PRISM BIOLAB CORPORATION (JP) 2012-08-30 WO disclosed
CN-101906102-B Beta-carboline alkaloid derivative, preparation method and application thereof UNIV CAPITAL MEDICAL 2012-08-29 CN disclosed
CN-101528673-B Method for producing asymmetric copper complex crystal SUMITOMO CO LTD 2012-08-01 CN disclosed
WO-2012055905-A1 PROCESS FOR THE MANUFACTURE OF DEGARELIX AND ITS INTERMEDIATES FERRING B.V. (NL) 2012-05-03 WO disclosed
EP-2447276-A1 Process for the manufacture of Degarelix and its intermediates Ferring B.V. (NL) 2012-05-02 EP disclosed
US-8153830-B2 Production method of asymmetric copper complex crystal SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-10 US disclosed
US-8138370-B2 Method of producing optically active α-amino acid benzyl esters SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-20 US disclosed
CN-102329376-A Cyclo(phenylalanine-N-methylleucyl-leucyl-N-methylleucyl-leucyl), and synthesis method and application thereof UNIV JINAN 2012-01-25 CN disclosed
CN-102320950-A Method for synthesizing acetic acid through carbonylation SHANGHAI HUAYI GROUP CO 2012-01-18 CN disclosed
CN-101565413-B Isoflavone derivative modified by acetylaminoacid benzyl ester, preparation method and application thereof PEKING UNIVERSITY (CN) 2011-12-28 CN disclosed
CN-102250202-A 1-paranitrophenyl-beta-carboline-3-formyl amine acid carbamates and synthesis method and use thereof UNIV CAPITAL MEDICAL 2011-11-23 CN disclosed
CN-102241674-A Synthesis method and antitumor activity evaluation of 1,1-dimethyl-beta-carboline-3-formacyl amino acid benzyl ester UNIV CAPITAL MEDICAL 2011-11-16 CN disclosed
CN-101597290-B Beta-carboline-3-formyl tryptophyl amine acid carbamate as well as preparation method and application thereof UNIV CAPITAL MEDICAL 2011-11-09 CN disclosed
CN-101658800-B Catalyst system for use in preparation of acetic acid and acetic anhydride or synchronous preparation of acetic acid and acetic anhydride and preparation method thereof SHANGHAI COKING & CHEM CORP 2011-11-02 CN disclosed
US-20110257028-A1 Method for selectively binding a substrate to sorbents by way of at least bivalent bonds INSTRACTION GMBH (DE) 2011-10-20 US disclosed
CN-101597289-B 2-tryptophanyl-Beta-tetrahydric carboline-3-formyol amino-acid benzyl ester and preparation method and application thereof UNIV CAPITAL MEDICAL 2011-09-21 CN disclosed
CN-101445550-B Synthetic method of pyroglutamyl small peptide UNIV XIAMEN 2011-04-20 CN disclosed
US-20110039208-A1 PHOTORESIST COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-02-17 US disclosed
US-20110039208-A1 PHOTORESIST COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-02-17 US disclosed
US-20110024292-A1 COMPOSITIONS AND METHODS FOR CYCLOFRUCTANS AS SEPARATION AGENTS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2011-02-03 US disclosed
US-20110024292-A1 COMPOSITIONS AND METHODS FOR CYCLOFRUCTANS AS SEPARATION AGENTS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2011-02-03 US disclosed
US-20110024292-A1 COMPOSITIONS AND METHODS FOR CYCLOFRUCTANS AS SEPARATION AGENTS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2011-02-03 US disclosed
CN-101927201-A Method for removing impurities from solution of acetic acid and/or acetic anhydride hydroformylation catalyst SHANGHAI COKING & CHEM CORP 2010-12-29 CN disclosed
CN-101497615-B Substituted purine, preparation and use in medicine ZHEJIANG MED XINCHANG PHARM 2010-12-15 CN disclosed
CN-101906102-A Beta-carboline alkaloid derivative, preparation method and application thereof UNIV CAPITAL MEDICAL 2010-12-08 CN disclosed
WO-2010105851-A1 PROBE COMPOUND FOR DETECTING AND ISOLATING ENZYMES AND MEANS AND METHODS USING THE SAME Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2010-09-23 WO disclosed
US-20100094036-A1 PRODUCTION METHOD OF ASYMMETRIC COPPER COMPLEX CRYSTAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-15 US disclosed
CN-101658800-A Catalyst system for use in preparation of acetic acid and acetic anhydride or synchronous preparation of acetic acid and acetic anhydride and preparation method thereof SHANGHAI COKING & CHEMICAL COR 2010-03-03 CN disclosed
CN-101659607-A Method for preparing acetic acid and acetic anhydride respectively or synchronously SHANGHAI COKING & CHEMICAL COR 2010-03-03 CN disclosed
US-20100010254-A1 METHOD OF PRODUCING OPTICALLY ACTIVE ALPHA-AMINO ACID BENZYL ESTERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-01-14 US disclosed
CN-101597290-A β-Ka Lin-3-formyl tryptophyl amino-acid benzyl ester and its production and application UNIV CAPITAL MEDICAL (CN) 2009-12-09 CN disclosed
CN-101597289-A 2-tryptophyl-beta-tetrahydro carboline-3-formyol amino-acid benzyl ester and its production and application UNIV CAPITAL MEDICAL (CN) 2009-12-09 CN disclosed
US-7625870-B2 Peptide substance restoring respiratory organs function “Access Bioscience” CJSC (RU) 2009-12-01 US disclosed
CN-101565413-A Isoflavone derivative modified by acetylaminoacid benzyl ester, preparation method and application thereof UNIV BEIJING (CN) 2009-10-28 CN disclosed
CN-101528673-A Method for producing asymmetric copper complex crystal SUMITOMO CHEMICAL CO (JP) 2009-09-09 CN disclosed
CN-101511776-A Process for production of optically active alpha-amino acid benzyl ester SUMITOMO CHEMICAL CO (JP) 2009-08-19 CN disclosed
CN-101497615-A Substituted purine, preparation and use in medicine XINCHANG PHARMACEUTICAL FACTORY ZHEJIANG MEDICINE CO LTD (CN) 2009-08-05 CN disclosed
EP-2078710-A1 METHOD FOR PRODUCING ASYMMETRIC COPPER COMPLEX CRYSTAL Sumitomo Chemical Company, Limited (JP) 2009-07-15 EP disclosed
CN-101445550-A Synthetic method of pyroglutamyl small peptide UNIV XIAMEN (CN) 2009-06-03 CN disclosed
EP-2062873-A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE ALPHA-AMINO ACID BENZYL ESTER Sumitomo Chemical Company, Limited (JP) 2009-05-27 EP disclosed
WO-2008134429-A1 CYSTEINE PROTEINASE INHIBITORS AND USES THEREOF THE SCRIPPS RESEARCH INSTITUTE (US) 2008-11-06 WO disclosed
US-20080274982-A1 Peptide Substance Restoring Respiratory Organs Function "ACCESS BIOSCIENCE" CJSC (RU) 2008-11-06 US disclosed
EP-1758922-B8 PEPTIDE SUBSTANCE RESTORING FUNCTION OF RESPIRATORY ORGANS ACCESS BIOSCIENCE CJSC (RU) 2008-05-07 EP disclosed
EP-1758922-B1 PEPTIDE SUBSTANCE RESTORING FUNCTION OF RESPIRATORY ORGANS SANKT PETERBURGSKAYA OBSCHESTV (RU) 2008-02-13 EP disclosed
CN-101090902-A Cgrp receptor antagonists MERCK & CO INC (US) 2007-12-19 CN disclosed
US-7262169-B1 Process for preparing peptide intermediates MERCK & CO., INC. (US) 2007-08-28 US disclosed
EP-1758922-A1 PEPTIDE SUBSTANCE RESTORING FUNCTION OF RESPIRATORY ORGANS SANKT-PETERBURGSKAYA OBSCHESTVENNAYA ORGANIZATSIYA "SANKT-PETERBURGSKIY INSTITUT BIOREGULYATSII I GERONTOLOGII SZO RAMN" (RU) 2007-03-07 EP disclosed
EP-1008592-B1 Cyclic amide derivatives which inhibit cathepsin K SEIKAGAKU KOGYO CO LTD (JP) 2006-02-01 EP disclosed
EP-1619189-A1 N-(3-acyl-2-hydroxyalkyl) cycloalkyl amide derivatives SEIKAGAKU CORPORATION (JP) 2006-01-25 EP disclosed
EP-1616867-A1 Hydroxycarboxylic acid derivatives SEIKAGAKU CORPORATION (JP) 2006-01-18 EP disclosed
EP-1616859-A1 Substituted cyclohexyl carboxylic acid compounds SEIKAGAKU CORPORATION (JP) 2006-01-18 EP disclosed
WO-2006001729-A1 PEPTIDE SUBSTANCE RESTORING RESPIRATORY ORGANS FUNCTION SANKT-PETERBURGSKAYA OBSCHESTVENNAYA ORGANIZATSIYA 'INSTITUT BIOREGULYATSII I GERONTOLOGII CZO RAMN' (RU) 2006-01-05 WO disclosed
US-6713502-B2 HEPATITIS C VIRUS INHIBITORS SMITHKLINE BEECHAM CORPORATION 2004-03-30 US disclosed
WO-2004011473-A1 ORGANOGERMANIUM COMPOUNDS AND METHODS FOR THEIR USE CHIROGEN PTY LIMITED (AU) 2004-02-05 WO disclosed
US-20040010030-A1 NOVEL ANTI-INFECTIVES SMITHKLINE BEECHAM CORPORATION 2004-01-15 US disclosed
US-20030133927-A1 Conjugates useful in the treatment of prostate cancer DEFEO-JONES DEBORAH (US) 2003-07-17 US disclosed
EP-1226158-B1 PROCESS FOR PREPARING PEPTIDE INTERMEDIATES MERCK SHARP & DOHME (GB) 2003-07-02 EP disclosed
EP-1278743-A4 NOVEL ANTI-INFECTIVES SMITHKLINE BEECHAM CORP (US) 2003-05-14 EP disclosed
US-6552166-B1 Oligopeptide is mixed with a salt of the anthracycline antibiotic in the presence of a carboxyl activating agent and a base MERCK & CO., INC. 2003-04-22 US disclosed
US-6552076-B2 Anticarcinogenic agents; controlling apoptosis MITOKOR 2003-04-22 US disclosed
EP-1278743-A1 NOVEL ANTI-INFECTIVES SmithKline Beecham Corporation (US) 2003-01-29 EP disclosed
US-20020173543-A1 Compounds for altering mitochondrial function and cellular responses MITOKOR 2002-11-21 US disclosed
US-6458781-B1 BLOCKERS CALCIUM CHANNEL ANTAGONISTS FOR STROKES, BRAIN DISORDERS WARNER-LAMBERT COMPANY 2002-10-01 US disclosed
EP-1226158-A1 PROCESS FOR PREPARING PEPTIDE INTERMEDIATES MERCK SHARP & DOHME LTD. (GB) 2002-07-31 EP disclosed
EP-1225918-A2 CONJUGATES USEFUL IN THE TREATMENT OF PROSTATE CANCER Merck & Co., Inc. (US) 2002-07-31 EP disclosed
US-6423689-B1 Peptidyl calcium channel blockers WARNER-LAMBERT COMPANY 2002-07-23 US disclosed
WO-2002048092-A2 COMPOUNDS FOR ALTERING MITOCHONDRIAL FUNCTION AND CELLULAR RESPONSES MITOKOR (US) 2002-06-20 WO disclosed
WO-2002039997-A2 ACE-2 MODULATING COMPOUNDS AND USE THEREOF MILLENNIUM PHARMACEUTICALS, INC. (US) 2002-05-23 WO disclosed
US-20020042375-A1 Method of treating cancer HEIMBROOK DAVID C (US) 2002-04-11 US disclosed
US-20020041880-A1 Method of treating cancer DEFEO-JONES DEBORAH (US) 2002-04-11 US disclosed
US-6362174-B1 ANALGESICS, ANTIISCHEMIC AGENTS, ANTIEOILEPTIC AGENTS WARNER-LAMBERT COMPANY 2002-03-26 US disclosed
US-6355611-B1 SODIUM SALT OF PROSTATE SPECIFIC ANTIGEN CONJUGATE COMPOUND; USEFUL IN TREATMENT OF PROSTATE CANCER AND BENIGN PROSTATIC HYPERPLASIA MERCK & CO., INC. 2002-03-12 US disclosed
US-20020028801-A1 Reduced dipeptide analogues as calcium channel antagonitsts RAFFERTY MICHAEL FRANCIS (US) 2002-03-07 US disclosed
WO-2001085720-A1 NOVEL ANTI-INFECTIVES SMITHKLINE BEECHAM CORPORATION (US) 2001-11-15 WO disclosed
US-6316440-B1 TREATMENT OF STROKE, HEAD TRAUMA, CEREBRAL ISCHEMIA, PAIN AND EPILEPSY WARNER-LAMBERT COMPANY 2001-11-13 US disclosed
EP-1135398-A1 CYANOPHOSPHONAMIDES AND METHOD FOR PREPARATION Monsanto Technology LLC (US) 2001-09-26 EP disclosed
WO-2001029065-A1 PROCESS FOR PREPARING PEPTIDE INTERMEDIATES MERCK SHARP & DOHME LIMITED (GB) 2001-04-26 WO disclosed
WO-2001028593-A2 CONJUGATES USEFUL IN THE TREATMENT OF PROSTATE CANCER MERCK & CO., INC. (US) 2001-04-26 WO disclosed
US-6218563-B1 Cyanophosphonamides and method for preparation MONSANTO COMPANY 2001-04-17 US disclosed
US-6117870-A USEFUL AS THERAPEUTIC DRUG OR PREVENTIVE DRUG OF ARTHRITIS AND RHEUMATISM DUE TO INCREASE OF BONE RESORPTION IN ADDITION TO BONE DISEASES SUCH AS OSTEOPOROSIS, HYPERCALCEMIA, AND PAGET'S DISEASE FUJIREBIO KABUSHIKI KAISHA (JP) 2000-09-12 US disclosed
EP-1008592-A2 Cyclic amide derivatives which inhibit cathepsin K Fujirebio Kabushiki Kaisha (JP) 2000-06-14 EP disclosed
WO-2000032611-A1 CYANOPHOSPHONAMIDES AND METHOD FOR PREPARATION MONSANTO TECHNOLOGY LLC (US) 2000-06-08 WO disclosed
WO-2000006559-A1 REDUCED DIPEPTIDE ANALOGUES AS CALCIUM CHANNEL ANTAGONISTS WARNER-LAMBERT COMPANY (US) 2000-02-10 WO disclosed
WO-1999055688-A1 SUBSTITUTED DIARYLALKYL AMIDES AS CALCIUM CHANNEL ANTAGONISTS WARNER-LAMBERT COMPANY (US) 1999-11-04 WO disclosed
EP-0948506-A1 CYANOPHOSPHONATE DERIVATIVES MONSANTO COMPANY (US) 1999-10-13 EP disclosed
EP-0948502-A1 CYANOPHOSPHORUS COMPOUNDS AND THEIR PREPARATION MONSANTO COMPANY (US) 1999-10-13 EP disclosed
EP-0941233-A2 ANTIVIRAL PEPTIDE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 1999-09-15 EP disclosed
US-5945082-A HERBICIDES, INSECTICIDES, FLAME RETARDANTS, PLASTICIZERS; CYANATION, SALT FORMATION, PHOSPHONATION, PHOSPHATING MONSANTO COMPANY (US) 1999-08-31 US disclosed
US-5935542-A Cyanphosphonate derivatives and method for their preparation MONSANTO COMPANY (US) 1999-08-10 US disclosed
WO-1998029419-A1 CYANOPHOSPHORUS COMPOUNDS AND THEIR PREPARATION MONSANTO COMPANY (US) 1998-07-09 WO disclosed
WO-1998029422-A1 CYANOPHOSPHONATE DERIVATIVES MONSANTO COMPANY (US) 1998-07-09 WO disclosed
WO-1998022496-A2 ANTIVIRAL PEPTIDE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 1998-05-28 WO disclosed
US-5719296-A THERAPY, PREVENTION OF AUTOIMMUNE DISEASES; PREVENTS PEPTIDE BINDING TO MAJOR HISTOCOMPATBILITY COMPLEX PROTEINS MERCK & CO., INC. (US) 1998-02-17 US disclosed
WO-1997016425-A1 NOVEL INHIBITORS OF PEPTIDE BINDING TO MHC CLASS II PROTEINS MERCK & CO., INC. (US) 1997-05-09 WO disclosed
EP-0671911-A4 CARBOXY-PEPTIDYL DERIVATIVES AS ANTIDEGENERATIVE ACTIVE AGENTS. MERCK & CO INC (US) 1996-08-21 EP disclosed
EP-0671911-A1 CARBOXY-PEPTIDYL DERIVATIVES AS ANTIDEGENERATIVE ACTIVE AGENTS MERCK & CO. INC. (US) 1995-09-20 EP disclosed
WO-1995008550-A1 ENDOTHELIN ANTAGONISTS ABBOTT LABORATORIES (US) 1995-03-30 WO disclosed
WO-1994012169-A1 CARBOXY-PEPTIDYL DERIVATIVES AS ANTIDEGENERATIVE ACTIVE AGENTS MERCK & CO., INC. (US) 1994-06-09 WO disclosed
EP-0320118-B1 PEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY BEECHAM GROUP PLC (GB) 1993-06-02 EP disclosed
WO-1993000359-A1 MODIFIED PEPTIDES TRANSPORTABLE INTO THE CENTRAL NERVOUS SYSTEM THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1993-01-07 WO disclosed
EP-0253882-A4 ACYLATED CYANAMIDE COMPOSITION. UNIV MINNESOTA (US) 1990-06-27 EP disclosed
US-4935404-A ANTIARTHRITIC AGENTS; RHEUMATIC DISEASES BEECHAM GROUP P.L.C. OF BEECHAM HOUSE (GB) 1990-06-19 US disclosed
EP-0320118-A2 Peptides with collagenase inhibiting activity BEECHAM GROUP PLC (GB) 1989-06-14 EP disclosed
EP-0126974-B1 CARBOXYALKYL PEPTIDE DERIVATIVES G.D. Searle & Co. (US) 1988-06-15 EP disclosed
EP-0253882-A1 ACYLATED CYANAMIDE COMPOSITION THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1988-01-27 EP disclosed
WO-1987004348-A1 ACYLATED CYANAMIDE COMPOSITION REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1987-07-30 WO disclosed
EP-0098865-A4 PEPTIDE SYNTHESIS AND AMINO ACID BLOCKING AGENTS. RESEARCH CORP (US) 1986-11-20 EP disclosed
US-4581167-A DIPEPTIDE INTERMEDIATE RESEARCH CORPORATION (US) 1986-04-08 US disclosed
US-4568666-A COLLAGENASE INHIBITORS, ANTIARTJRITIC AGENTS G. D. SEARLE & CO. (US) 1986-02-04 US disclosed
US-4511504-A COLLAGENASE INHIBITORS G.D. SEARLE & CO. (US) 1985-04-16 US disclosed
US-4508657-A Peptide synthesis and amino acid blocking agents RESEARCH CORPORATION (US) 1985-04-02 US disclosed
EP-0126974-A1 Carboxyalkyl peptide derivatives G.D. Searle & Co. (US) 1984-12-05 EP disclosed
US-4460503-A OLIGO AND POLYPEPTIDES INSTITUT PASTEUR (FR) 1984-07-17 US disclosed
EP-0098865-A1 PEPTIDE SYNTHESIS AND AMINO ACID BLOCKING AGENTS. RESEARCH CORP (US) 1984-01-25 EP disclosed
WO-1983002448-A1 PEPTIDE SYNTHESIS AND AMINO ACID BLOCKING AGENTS RESEARCH CORP (US) 1983-07-21 WO disclosed
US-4394519-A N-(INDENYLMETHOXYCARBONYL) AMINO ACIDS RESEARCH CORPORATION (US) 1983-07-19 US disclosed
US-4064236-A Peptide carbazates and pharmaceutical composition MERCK & CO., INC. (US) 1977-12-20 US disclosed
US-4064236-A Peptide carbazates and pharmaceutical composition MERCK & CO., INC. (US) 1977-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (16 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020173543-A1 Compounds for altering mitochondrial function and cellular responses UQCRC1, UQCRC2, NDUFAB1 ALDH1A1 1003/4885ANPEP 4782/4885RNPEP 4450/4885
US-20030133927-A1 Conjugates useful in the treatment of prostate cancer BCL2, BCL2L10, BCL2L13 ALDH1A1 3095/4885ANPEP 148/4885RNPEP 145/4885
US-20110257028-A1 Method for selectively binding a substrate to sorbents by way of at least bivalent bonds SPR, ABCG2, SHBG ALDH1A1 2479/4885ANPEP 1844/4885RNPEP 998/4885
US-20020042375-A1 Method of treating cancer ACP3, KLK3, FOLH1 ALDH1A1 86/4885ANPEP 352/4885RNPEP 508/4885
US-20110024292-A1 COMPOSITIONS AND METHODS FOR CYCLOFRUCTANS AS SEPARATION AGENTS PAICS, DCXR, PFAS ALDH1A1 1565/4885ANPEP 448/4885RNPEP 712/4885
US-20140051706-A1 ALPHA HELIX MIMETICS AND METHODS RELATING THERETO COL1A1, PLOD3, THPO ALDH1A1 1615/4885ANPEP 3146/4885RNPEP 3245/4885
US-20160145301-A1 PROCESS FOR THE MANUFACTURE OF DEGARELIX AND ITS INTERMEDIATES VIP, HABP2, DPP9 ALDH1A1 2182/4885ANPEP 5/4885RNPEP 56/4885
US-11040939-B1 N-transfer reagent and method for preparing the same and its application DNTT, NNMT, NMT1 ALDH1A1 1050/4885ANPEP 201/4885RNPEP 264/4885
US-20020028801-A1 Reduced dipeptide analogues as calcium channel antagonitsts CACNA1E, RYR1, CACNA1B ALDH1A1 3308/4885ANPEP 676/4885RNPEP 1628/4885
US-20120231972-A1 Probe Compound for Detecting and Isolating Enzymes and Means and Methods Using the Same SI, GUSB, MPI ALDH1A1 194/4885ANPEP 32/4885RNPEP 93/4885
US-20080274982-A1 Peptide Substance Restoring Respiratory Organs Function GLUL, ENPEP, VIP ALDH1A1 1863/4885ANPEP 9/4885RNPEP 20/4885
US-20130281661-A1 PROCESS FOR THE MANUFACTURE OF DEGARELIX AND ITS INTERMEDIATES HM13, HABP2, DPP9 ALDH1A1 2110/4885ANPEP 10/4885RNPEP 66/4885
US-20100094036-A1 PRODUCTION METHOD OF ASYMMETRIC COPPER COMPLEX CRYSTAL ADH1A, ADH1C, ALDH3A1 ALDH1A1 31/4885ANPEP 1858/4885RNPEP 878/4885
US-20100010254-A1 METHOD OF PRODUCING OPTICALLY ACTIVE ALPHA-AMINO ACID BENZYL ESTERS BCAT1, BCAT2, AADAT ALDH1A1 186/4885ANPEP 19/4885RNPEP 63/4885
US-20040010030-A1 NOVEL ANTI-INFECTIVES CTSL, MMP8, SERPINB1 ALDH1A1 4350/4885ANPEP 751/4885RNPEP 286/4885
US-20020041880-A1 Method of treating cancer ACP3, FOLH1, KLK3 ALDH1A1 296/4885ANPEP 223/4885RNPEP 298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.