Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 14/20 | 0.89 |
| ▸ | PPIA | P62937 | 5/20 | 0.89 |
| ▸ | FKBP1B | P68106 | 2/20 | 0.89 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.89 |
| ▸ | ABCC2 | Q92887 | 2/20 | 0.89 |
| ▸ | PPP3CA | Q08209 | 2/20 | 0.89 |
| ▸ | MEN1 | O00255 | 1/20 | 0.89 |
| ▸ | NPC1 | O15118 | 1/20 | 0.89 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.89 |
| ▸ | GMNN | O75496 | 1/20 | 0.89 |
| ▸ | USP2 | O75604 | 1/20 | 0.89 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.89 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.89 |
| ▸ | LMNA | P02545 | 1/20 | 0.89 |
| ▸ | POLB | P06746 | 1/20 | 0.89 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.89 |
| ▸ | MAPT | P10636 | 1/20 | 0.89 |
| ▸ | RARB | P10826 | 1/20 | 0.89 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.89 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.89 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22033395 | 1.00 | ABCB1 (0.89) | ABCB1PPIAFKBP1BABCC1ABCC2 | |
| SCHEMBL19646863 | 1.00 | ABCB1 (0.89) | ABCB1PPIAFKBP1BABCC1ABCC2 | |
| SCHEMBL16596082 | 1.00 | ABCB1 (0.89) | ABCB1PPIAFKBP1BABCC1ABCC2 | |
| SCHEMBL1708943 | 0.98 | ABCB1 (0.89) | ABCB1PPIAFKBP1BABCC1ABCC2 | |
| SCHEMBL101371 | 0.98 | ABCB1 (0.89) | ABCB1PPIAFKBP1BABCC1ABCC2 | |
| SCHEMBL18163232 | 0.98 | ABCB1 (0.89) | ABCB1PPIAFKBP1BABCC1ABCC2 | |
| SCHEMBL439348 | 0.96 | ABCB1 (0.89) | ABCB1PPIAFKBP1BABCC1ABCC2 | |
| SCHEMBL22032784 | 0.96 | ABCB1 (0.89) | ABCB1PPIAFKBP1BABCC1ABCC2 | |
| Cyclosporine SCHEMBL25083206 | 0.94 | ABCB1 (1.00) | ABCB1PPIAFKBP1BABCC1ABCC2 | |
| Cyclosporine SCHEMBL24239446 | 0.94 | ABCB1 (1.00) | ABCB1PPIAFKBP1BABCC1ABCC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 502 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115266996-B | Analysis method and application of related substances in cyclosporine A preparation | 兆科（广州）眼科药物有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-115803063-A | Nanolipid protein-polypeptide conjugates and compositions, systems, and methods of use thereof | 基因泰克公司 | 2023-03-14 | — | — | CN | claimed |
| CN-115266996-A | Analysis method and application of related substances in cyclosporin A preparation | 兆科（广州）眼科药物有限公司 | 2022-11-01 | — | — | CN | claimed |
| EP-2931299-B1 | NOVEL PHARMACEUTICAL FORMULATIONS AND THEIR USE IN THE TREATMENT OF PERIODONTAL DISEASE | PERIOC LTD (GB) | 2019-02-06 | — | — | EP | claimed |
| US-20160304554-A1 | PROCESS FOR THE MANUFACTURE OF CYCLIC UNDECAPEPTIDES | NOVARTIS PHARMA AG (CH) | 2016-10-20 | — | — | US | claimed |
| WO-2015193673-A1 | NOVEL PHARMACEUTICAL FORMULATIONS AND THEIR USE IN THE TREATMENT OF PERIODONTAL DISEASE | PERIOC LIMITED (GB) | 2015-12-23 | — | — | WO | claimed |
| US-20150313959-A1 | NOVEL PHARMACEUTICAL FORMULATIONS AND THEIR USE IN THE TREATMENT OF PERIODONTAL DISEASE | PERIOC LTD (GB) | 2015-11-05 | — | — | US | claimed |
| EP-2931299-A1 | NOVEL PHARMACEUTICAL FORMULATIONS AND THEIR USE IN THE TREATMENT OF PERIODONTAL DISEASE | Perioc Ltd. (GB) | 2015-10-21 | — | — | EP | claimed |
| US-20150087808-A1 | PROCESS FOR THE MANUFACTURE OF CYCLIC UNDECAPEPTIDES | NOVARTIS AG (CH) | 2015-03-26 | — | — | US | claimed |
| WO-2014091239-A1 | NOVEL PHARMACEUTICAL FORMULATIONS AND THEIR USE IN THE TREATMENT OF PERIODONTAL DISEASE | PERIOC LTD (GB) | 2014-06-19 | — | — | WO | claimed |
| WO-1997018828-A1 | INHIBITORS OF CYCLOPHILIN ROTAMASE ACTIVITY | GUILFORD PHARMACEUTICALS INC. (US) | 1997-05-29 | — | — | WO | claimed |
| US-5616595-A | CONCENTRATION, SOLUBILIZING, DIAFILTRATION IN A CLOSED RECIRCULATION SYSTEM | ABBOTT LABORATORIES (US) | 1997-04-01 | — | — | US | claimed |
| WO-1996040089-A2 | AEROSOL DRUG FORMULATIONS CONTAINING VEGETABLE OILS | ABBOTT LABORATORIES (US) | 1996-12-19 | — | — | WO | claimed |
| WO-1996040758-A1 | PROCESS FOR RECOVERING WATER-INSOLUBLE COMPOUNDS FROM A FERMENTATION BROTH | ABBOTT LABORATORIES (US) | 1996-12-19 | — | — | WO | claimed |
| US-5382655-A | Process for the purification of cyclosporin A | BIOGAL GYOGYSZERARUGYAR RT (HU) | 1995-01-17 | — | — | US | claimed |
| EP-0379708-B1 | Fungi strain Tolypocladiam varium and process for obtaining complexes of antibiotic cyclosporin and/or its components | BIOGAL GYOGYSZERGYAR (HU) | 1994-12-07 | — | — | EP | claimed |
| US-5051402-A | Fungicides, immunosuppressants and antiphlogistic agents | SANKYO COMPANY, LIMITED (JP) | 1991-09-24 | — | — | US | claimed |
| EP-0379708-A1 | Fungi strain Tolypocladiam varium and process for obtaining complexes of antibiotic cyclosporin and/or its components | BIOGAL GYOGYSZERGYAR (HU) | 1990-08-01 | — | — | EP | claimed |
| WO-1990000389-A1 | FREEZE-DRIED LIPOSOME COMPOSITIONS CONTAINING CYCLOSPORIN | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1990-01-25 | — | — | WO | claimed |
| US-4727035-A | RADIOACTIVE OR FLUORESCENT LABELS | SANDOZ LTD. (CH) | 1988-02-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150313959-A1 | NOVEL PHARMACEUTICAL FORMULATIONS AND THEIR USE IN THE TREATMENT OF PERIODONTAL DISEASE | PPIL1, PPIG, PPID | ABCB1 158/4885PPIA 12/4885FKBP1B 19/4885 |
| US-20150087808-A1 | PROCESS FOR THE MANUFACTURE OF CYCLIC UNDECAPEPTIDES | UMPS, SAMHD1, NPEPPS | ABCB1 1583/4885PPIA 951/4885FKBP1B 1288/4885 |
| US-20160304554-A1 | PROCESS FOR THE MANUFACTURE OF CYCLIC UNDECAPEPTIDES | UMPS, SAMHD1, NPEPPS | ABCB1 1583/4885PPIA 951/4885FKBP1B 1288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.