Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 16/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4393521 | 0.88 | RAF1 (0.43) | C1RNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL4263346 | 0.85 | C1R (0.43) | C1RNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL4259369 | 0.78 | C1R (0.48) | C1RNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL4262124 | 0.78 | C1R (0.40) | C1RNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL3453537 | 0.77 | C1R (0.70) | C1RNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL3453116 | 0.74 | C1R (0.67) | C1RNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7034176 | 0.74 | C1R (0.43) | C1RNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL4260494 | 0.74 | C1R (0.46) | C1RNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL4259213 | 0.74 | C1R (0.46) | C1RNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL4268147 | 0.72 | C1R (0.47) | C1RNPC1ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090029978-A1 | THIENO-(1,3)-OXAZIN-4-ONES WITH LIPASE INHIBITING ACTIVITY | ALIZYME THERAPEUTICS LIMITED (GB) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029978-A1 | THIENO-(1,3)-OXAZIN-4-ONES WITH LIPASE INHIBITING ACTIVITY | LPL, LIPE, LIPC | C1R 3110/4885NPC1 725/4885ALDH1A1 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.