Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 16/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437488 | 0.88 | MCHR1 (0.58) | MCHR1ASIC3 | |
| SCHEMBL437548 | 0.81 | MCHR1 (0.49) | MCHR1NOS3NOS1NOS2ASIC3 | |
| SCHEMBL439615 | 0.81 | NR4A2 (0.59) | MCHR1ASIC3 | |
| SCHEMBL439523 | 0.81 | MCHR1 (0.57) | MCHR1 | |
| SCHEMBL441893 | 0.79 | ACHE (0.44) | MCHR1KCNH2 | |
| SCHEMBL441586 | 0.79 | KDM4E (0.60) | MCHR1ASIC3 | |
| SCHEMBL441705 | 0.77 | CTSS (0.45) | MCHR1 | |
| SCHEMBL442339 | 0.75 | NR4A2 (0.64) | — | |
| SCHEMBL30682591 | 0.75 | NR4A2 (0.64) | — | |
| SCHEMBL438576 | 0.74 | MCHR1 (0.49) | MCHR1NOS3NOS1NOS2ASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |