Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SCN4A | P35499 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436437 | 0.90 | MCHR1 (0.51) | CTSSCTSKNPC1RAB9AGMNN | |
| SCHEMBL441893 | 0.83 | ACHE (0.44) | CYP1A2CYP3A4SMN1; SMN2HSD17B10MCHR1 | |
| SCHEMBL439523 | 0.80 | MCHR1 (0.57) | CTSSCTSKMCHR1 | |
| SCHEMBL439632 | 0.79 | NR4A2 (0.54) | NPC1RAB9AGMNNUSP2LMNA | |
| SCHEMBL439432 | 0.77 | MCHR1 (0.49) | MCHR1 | |
| SCHEMBL437548 | 0.75 | MCHR1 (0.49) | MCHR1 | |
| SCHEMBL439615 | 0.75 | NR4A2 (0.59) | MCHR1 | |
| SCHEMBL437914 | 0.73 | CTSS (0.41) | CTSSCTSKMCHR1 | |
| SCHEMBL441586 | 0.72 | KDM4E (0.60) | GAASMN1; SMN2HSD17B10MCHR1MAPK1 | |
| SCHEMBL23283481 | 0.72 | ACHE (0.46) | NPC1RAB9ALMNACYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |