SCHEMBL4396001

SCHEMBL4396001

CC(C)c1nccn1CCCN

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.55
TLR8 Q9NR97 2/20 0.42
ALDH1A1 P00352 1/20 0.41
POLB P06746 1/20 0.41
KMT2A Q03164 1/20 0.41
KCNH2 Q12809 3/20 0.39
NMT1 P30419 1/20 0.37
CYP2D6 P10635 1/20 0.36
TSHR P16473 1/20 0.36
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
ARG1 P05089 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3038968 0.89 SMN1; SMN2 (0.63) SMN1; SMN2TLR8ALDH1A1POLBKMT2A
Hydrochloric Acid SCHEMBL5133311 0.87 SMN1; SMN2 (0.66) SMN1; SMN2TLR8ALDH1A1POLBKMT2A
SCHEMBL14416001 0.86 SMN1; SMN2 (0.45) SMN1; SMN2TLR8ALDH1A1POLBKMT2A
SCHEMBL25857294 0.86 SMN1; SMN2 (0.55) SMN1; SMN2TLR8ALDH1A1POLBKMT2A
SCHEMBL12424656 0.84 ALDH1A1 (0.59) SMN1; SMN2TLR8ALDH1A1POLBKMT2A
SCHEMBL25067265 0.82 TLR8 (0.59) SMN1; SMN2TLR8ALDH1A1POLBKMT2A
SCHEMBL25067256 0.82 SMN1; SMN2 (0.55) SMN1; SMN2TLR8ALDH1A1POLBKMT2A
SCHEMBL25857292 0.81 SMN1; SMN2 (0.58) SMN1; SMN2KCNH2NMT1CYP2D6TSHR
SCHEMBL26027171 0.81 SMN1; SMN2 (0.53) SMN1; SMN2TLR8KCNH2CYP2D6TSHR
SCHEMBL18250324 0.81 TLR8 (0.57) SMN1; SMN2TLR8ALDH1A1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11471821-B2 Process for biogas upgradation INDIAN OIL CORPORATION LIMITED (IN) 2022-10-18 US claimed
EP-1971600-B1 ISOXAZOLE DERIVATIVES AND USE THEREOF SK BIOPHARMACEUTICALS CO LTD (KR) 2013-08-21 EP claimed
US-20090131336-A1 Isoxazole Derivatives and Use Thereof SK BIOPHARMACEUTICALS CO., LTD. (KR) 2009-05-21 US claimed
EP-1971600-A1 ISOXAZOLE DERIVATIVES AND USE THEREOF SK Holdings Co., Ltd. (KR) 2008-09-24 EP claimed
WO-2007078113-A1 ISOXAZOLE DERIVATIVES AND USE THEREOF SK HOLDINGS CO., LTD. (KR) 2007-07-12 WO claimed
WO-2023158738-A2 LIPID NANOPARTICLES FOR DELIVERY TO THE EYE OR EAR TRUSTEES OF TUFTS COLLEGE (US) 2023-08-24 WO disclosed
US-20230212629-A1 COMPOSITIONS AND METHODS FOR PRODUCING CIRCULAR POLYRIBONUCLEOTIDES FLAGSHIP PIONEERING INNOVATIONS VI, LLC 2023-07-06 US disclosed
US-11607646-B2 Process for CO2 capture from gaseous streams INDIAN OIL CORPORATION LIMITED (IN) 2023-03-21 US disclosed
US-11471821-B2 Process for biogas upgradation INDIAN OIL CORPORATION LIMITED (IN) 2022-10-18 US disclosed
US-20210322920-A1 PROCESS FOR BIOGAS UPGRADATION INIDAN OIL CORPORATION LIMITED (IN) 2021-10-21 US disclosed
EP-3895783-A1 PROCESS FOR BIOGAS UPGRADATION Indian Oil Corporation Limited (IN) 2021-10-20 EP disclosed
EP-3620225-B1 PROCESS FOR CO2 CAPTURE FROM GASEOUS STREAMS INDIAN OIL CORP LTD (IN) 2021-04-28 EP disclosed
US-20200070091-A1 PROCESS FOR CO2 CAPTURE FROM GASEOUS STREAMS INDIAN OIL CORPORATION LIMITED (IN) 2020-03-05 US disclosed
EP-1971600-B1 ISOXAZOLE DERIVATIVES AND USE THEREOF SK BIOPHARMACEUTICALS CO LTD (KR) 2013-08-21 EP disclosed
US-20090131336-A1 Isoxazole Derivatives and Use Thereof SK BIOPHARMACEUTICALS CO., LTD. (KR) 2009-05-21 US disclosed
EP-1971600-A1 ISOXAZOLE DERIVATIVES AND USE THEREOF SK Holdings Co., Ltd. (KR) 2008-09-24 EP disclosed
WO-2007078113-A1 ISOXAZOLE DERIVATIVES AND USE THEREOF SK HOLDINGS CO., LTD. (KR) 2007-07-12 WO disclosed
EP-0188999-B1 CATIONIC REACTION PRODUCTS FROM 1-AMINOALKYL IMIDAZOLE COMPOUNDS AND EPIHALOGEN HYDRINS CIBA-GEIGY AG (CH) 1989-05-31 EP disclosed
US-4705865-A Cationic reaction products formed from 1-aminoalkyl-imidazole compounds and epihalohydrins CIBA-GEIGY CORPORATION (US) 1987-11-10 US disclosed
EP-0188999-A1 Cationic reaction products from 1-aminoalkyl imidazole compounds and epihalogen hydrins CIBA-GEIGY AG (CH) 1986-07-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090131336-A1 Isoxazole Derivatives and Use Thereof WNT3A, WNT1, WNT3 SMN1; SMN2 3980/4885TLR8 2096/4885ALDH1A1 706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.