Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | ARG1 | P05089 | 2/20 | 0.51 |
| ▸ | ARG2 | P78540 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4396691 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2HIF1AARG1ARG2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4398176 | 0.98 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1AARG1ARG2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4398174 | 0.98 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1AARG1ARG2ALDH1A1 | |
| SCHEMBL9551389 | 0.88 | HTT (0.54) | SMN1; SMN2HIF1AARG1ARG2ALDH1A1 | |
| SCHEMBL9551388 | 0.88 | HTT (0.54) | SMN1; SMN2HIF1AARG1ARG2ALDH1A1 | |
| SCHEMBL12583561 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1AARG1ARG2ALDH1A1 | |
| SCHEMBL8351006 | 0.83 | SMN1; SMN2 (0.69) | SMN1; SMN2HIF1AARG1ARG2TSHR | |
| SCHEMBL27420773 | 0.83 | ALDH1A1 (0.46) | SMN1; SMN2HIF1AARG1ARG2ALDH1A1 | |
| SCHEMBL8903660 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2HIF1AARG1ARG2ALDH1A1 | |
| SCHEMBL28910344 | 0.79 | PPARA (0.42) | ARG1ARG2ALDH1A1TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716524-B2 | Optically active quaternary ammonium salt having axial asymmetry and process for producing a-amino acid and derivative thereof with the same | NAGASE & CO., LTD (JP) | 2014-05-06 | — | — | US | disclosed |
| US-8716524-B2 | Optically active quaternary ammonium salt having axial asymmetry and process for producing a-amino acid and derivative thereof with the same | NAGASE & CO., LTD (JP) | 2014-05-06 | — | — | US | disclosed |
| US-20110152562-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING a-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME | NAGASE & CO., LTD. (JP) | 2011-06-23 | — | — | US | disclosed |
| US-20110152562-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING a-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME | NAGASE & CO., LTD. (JP) | 2011-06-23 | — | — | US | disclosed |
| US-7928224-B2 | Optically active quaternary ammonium salt having axial asymmetry and process for producing α-amino acid and derivative thereof with the same | NAGASE & CO., LTD (JP) | 2011-04-19 | — | — | US | disclosed |
| US-7928224-B2 | Optically active quaternary ammonium salt having axial asymmetry and process for producing α-amino acid and derivative thereof with the same | NAGASE & CO., LTD (JP) | 2011-04-19 | — | — | US | disclosed |
| US-7511039-B2 | β-sheet mimetics and use thereof as inhibitors of biologically active peptides or proteins | MYRIAD GENETICS, INC. (US) | 2009-03-31 | — | — | US | disclosed |
| US-20070161624-A1 | Optically active quaternary ammonium salt having axial asymmetry and process for producing alpha-amino acid and derivative thereof with the same | KISHIDA CHEMICAL CO., LTD. (JP) | 2007-07-12 | — | — | US | disclosed |
| US-20070161624-A1 | Optically active quaternary ammonium salt having axial asymmetry and process for producing alpha-amino acid and derivative thereof with the same | KISHIDA CHEMICAL CO., LTD. (JP) | 2007-07-12 | — | — | US | disclosed |
| US-20070135654-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING alpha-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME | NAGASE & CO., LTD (JP) | 2007-06-14 | — | — | US | disclosed |
| EP-0817642-A1 | $g(b)-SHEET MIMETICS AND USE THEREOF AS INHIBITORS OF BIOLOGICALLY ACTIVE PEPTIDES OR PROTEINS | MOLECUMETICS, LTD. (US) | 1998-01-14 | — | — | EP | disclosed |
| EP-0815123-A1 | $g(b)-SHEET MIMETICS AND USE THEREOF AS PROTEASE INHIBITORS | MOLECUMETICS, LTD. (US) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996030035-A1 | β-SHEET MIMETICS AND USE THEREOF AS INHIBITORS OF BIOLOGICALLY ACTIVE PEPTIDES OR PROTEINS | MOLECUMETICS LTD. (US) | 1996-10-03 | — | — | WO | disclosed |
| WO-1996030396-A1 | β-SHEET MIMETICS AND USE THEREOF AS PROTEASE INHIBITORS | MOLECUMETICS LTD. (US) | 1996-10-03 | — | — | WO | disclosed |
| US-5268476-A | Substituted 10bH-oxazolo[3,2-c] [1,3] benzoxazine-2(3H), 5-diones | ABBOTT LABORATORIES (US) | 1993-12-07 | — | — | US | disclosed |
| US-5164388-A | Hypotensive agents, treatment of congestive heart failure | ABBOTT LABORATORIES (US) | 1992-11-17 | — | — | US | disclosed |
| US-5153358-A | Process for the preparation of alpha-alkylated alpha-amino acids and alpha-halogenated alpha-amino acids | ABBOTT LABORATORIES (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0439556-A1 | HETEROCYCLIC PEPTIDE RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1991-08-07 | — | — | EP | disclosed |
| WO-1990004917-A1 | HETEROCYCLIC PEPTIDE RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1990-05-17 | — | — | WO | disclosed |
| EP-0365992-A1 | Heterocyclic peptide renin inhibitors | ABBOTT LABORATORIES (US) | 1990-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135654-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING alpha-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME | BCAT1, BCAT2, AADAT | SMN1; SMN2 3390/4885HIF1A 1262/4885ARG1 181/4885 |
| US-20110152562-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING a-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME | BCAT1, AADAT, BCAT2 | SMN1; SMN2 3497/4885HIF1A 1501/4885ARG1 125/4885 |
| US-20070161624-A1 | Optically active quaternary ammonium salt having axial asymmetry and process for producing alpha-amino acid and derivative thereof with the same | BCAT1, BCAT2, AADAT | SMN1; SMN2 3390/4885HIF1A 1262/4885ARG1 181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.