Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5852336 | 0.84 | MMP1 (0.52) | HCAR2LMNATDP1L3MBTL1 | |
| SCHEMBL31606878 | 0.83 | HCAR2 (0.61) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL8509226 | 0.81 | CYP17A1 (0.48) | LMNAALDH1A1TDP1KMT2ACYP1A2 | |
| SCHEMBL7545947 | 0.80 | LMNA (0.57) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL43607 | 0.80 | HCAR2 (0.38) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL337503 | 0.79 | HCAR2 (0.89) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL9395526 | 0.79 | HCAR2 (0.69) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL337504 | 0.79 | HCAR2 (0.89) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL357565 | 0.79 | HCAR2 (0.89) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL42978 | 0.79 | CA12 (0.50) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250092008-A1 | PROCESS FOR MAKING AN EP4 ANTAGONIST | ONO PHARMACEUTICAL CO., LTD. (JP) | 2025-03-20 | — | — | US | claimed |
| CN-119219500-A | Intermediate of 2, 3-dimethylcyclopropylcarboxylic acid and synthetic method thereof | 南通诺泰生物医药技术有限公司 | 2024-12-31 | — | — | CN | claimed |
| EP-4384509-A1 | PROCESS FOR MAKING AN EP4 ANTAGONIST | ONO Pharmaceutical Co., Ltd. (JP) | 2024-06-19 | — | — | EP | claimed |
| WO-2023017813-A1 | PROCESS FOR MAKING AN EP4 ANTAGONIST | ONO PHARMACEUTICAL CO., LTD. (JP) | 2023-02-16 | — | — | WO | claimed |
| CN-106831764-B | A kind of Indoli zine derivatives and preparation method thereof | 苏州大学 | 2018-11-02 | — | — | CN | claimed |
| CN-106831764-A | A kind of Indoli zine derivatives and preparation method thereof | 苏州大学 | 2017-06-13 | — | — | CN | claimed |
| CN-105884647-A | Synthesis method of 3-hydroxyl diazoester intermediate alkyne compound | 湖北科技学院 | 2016-08-24 | — | — | CN | claimed |
| US-20130165696-A1 | NOVEL PROCESSES FOR THE PREPARATION OF PHENYLCYCLOPROPYLAMINE DERIVATIVES AND USE THEREOF FOR PREPARING TICAGRELOR | ACTAVIS GROUP PTC EHF (IS) | 2013-06-27 | — | — | US | claimed |
| EP-2588441-A2 | NOVEL PROCESSES FOR THE PREPARATION OF PHENYLCYCLOPROPYLAMINE DERIVATIVES AND USE THEREOF FOR PREPARING TICAGRELOR | Actavis Group Ptc Ehf (IS) | 2013-05-08 | — | — | EP | claimed |
| WO-2012001531-A2 | NOVEL PROCESSES FOR THE PREPARATION OF PHENYLCYCLOPROPYLAMINE DERIVATIVES AND USE THEREOF FOR PREPARING TICAGRELOR | ACTAVIS GROUP PTC EHF (IS) | 2012-01-05 | — | — | WO | claimed |
| WO-2011157444-A1 | FUNCTIONALIZED MATERIALS BY CATALYZED CARBENE COPOLYMERIZATION | STICHTING DUTCH POLYMER INSTITUTE (NL) | 2011-12-22 | — | — | WO | claimed |
| EP-2397509-A1 | Functionalized materials by catalyzed carbene copolymerization | Stichting Dutch Polymer Institute (NL) | 2011-12-21 | — | — | EP | claimed |
| EP-4688790-A1 | MACROCYCLIC RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| EP-4688789-A1 | MACROCYCLIC RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| US-20260028353-A1 | MACROCYCLIC RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT | 2026-01-29 | — | — | US | disclosed |
| US-20250346585-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2025-11-13 | — | — | US | disclosed |
| US-4548815-A | SYNERGISTIC MIXTURE OF AN OXAPENICILLIN AND A PENICILLIN | BEECHAM GROUP P.L.C. (GB) | 1985-10-22 | — | — | US | disclosed |
| US-4444685-A | Stereospecific synthesis of thienamycin from penicillin | MERCK & CO., INC. (US) | 1984-04-24 | — | — | US | disclosed |
| US-4361512-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1982-11-30 | — | — | US | disclosed |
| US-4228174-A | ANTIBIOTICS | BEECHAM GROUP LIMITED (GB) | 1980-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260028353-A1 | MACROCYCLIC RAS INHIBITORS | KRAS, NRAS, HRAS | HCAR2 4158/4885LMNA 2273/4885ALDH1A1 3620/4885 |
| US-20250346585-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | C5, C1S, C9 | HCAR2 3050/4885LMNA 991/4885ALDH1A1 1707/4885 |
| US-20250092008-A1 | PROCESS FOR MAKING AN EP4 ANTAGONIST | PTGER4, LTB4R2, EPB41 | HCAR2 61/4885LMNA 2457/4885ALDH1A1 1405/4885 |
| US-20130165696-A1 | NOVEL PROCESSES FOR THE PREPARATION OF PHENYLCYCLOPROPYLAMINE DERIVATIVES AND USE THEREOF FOR PREPARING TICAGRELOR | THPO, P2RY4, TBXA2R | HCAR2 2713/4885LMNA 3776/4885ALDH1A1 1717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.