Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43077 | 0.86 | GAA (0.44) | HCAR2TDP1ALDH1A1 | |
| SCHEMBL43819 | 0.80 | GABRA1 (0.33) | HCAR2LMNAPOLBALDH1A1CYP1A2 | |
| SCHEMBL43967 | 0.80 | HCAR2 (0.59) | HCAR2LMNAPOLBTDP1ALDH1A1 | |
| SCHEMBL9784740 | 0.76 | RAB9A (0.49) | POLBALDH1A1MAPT | |
| SCHEMBL43788 | 0.75 | ALDH1A1 (0.58) | GRIN2BPOLBTDP1ALDH1A1MEN1 | |
| SCHEMBL18641307 | 0.75 | GRIN2B (0.41) | GRIN2BLMNAPOLBTDP1ALDH1A1 | |
| SCHEMBL17283451 | 0.75 | ALDH1A1 (0.58) | GRIN2BPOLBTDP1ALDH1A1MAPT | |
| SCHEMBL707570 | 0.75 | MET (0.36) | HCAR2LMNAPOLBALDH1A1CYP1A2 | |
| SCHEMBL30275198 | 0.71 | TOP2A (0.49) | GRIN2BALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8509226 | 0.70 | CYP17A1 (0.48) | LMNATDP1ALDH1A1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011157444-A1 | FUNCTIONALIZED MATERIALS BY CATALYZED CARBENE COPOLYMERIZATION | STICHTING DUTCH POLYMER INSTITUTE (NL) | 2011-12-22 | — | — | WO | disclosed |