Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1675682 | 0.79 | KMT2A (0.74) | KMT2AFAAHL3MBTL1EPHX2MEN1 | |
| SCHEMBL1669171 | 0.74 | ALDH1A1 (0.50) | KMT2AL3MBTL1MEN1 | |
| SCHEMBL1675968 | 0.73 | KMT2A (0.57) | KMT2AFAAHL3MBTL1EPHX2MEN1 | |
| SCHEMBL8594052 | 0.72 | AKR1C3 (0.53) | KMT2AL3MBTL1 | |
| SCHEMBL19375483 | 0.70 | KMT2A (0.56) | KMT2AFAAHEPHX2HSD11B1 | |
| SCHEMBL13634586 | 0.69 | NPC1 (0.56) | KMT2AFAAHEPHX2MEN1CNR2 | |
| SCHEMBL4410933 | 0.68 | FAAH (0.46) | KMT2AFAAHL3MBTL1EPHX2MEN1 | |
| Benzophenone SCHEMBL29110866 | 0.68 | ALDH1A1 (0.70) | KMT2AFAAHL3MBTL1EPHX2MEN1 | |
| SCHEMBL15051964 | 0.67 | KMT2A (0.65) | KMT2AFAAHEPHX2HSD11B1 | |
| SCHEMBL580738 | 0.66 | AKR1C3 (0.53) | KMT2AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1796657-B1 | N-2 ADAMANTANYL-2-PHENOXY-ACETAMIDE DERIVATIVES AS 11-BETA HYDROXYSTEROID DEHYDROGENASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-12-23 | — | — | EP | disclosed |