Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4410964 | 0.85 | HSD11B1 (0.53) | — | |
| Hydrochloric Acid SCHEMBL9343553 | 0.73 | HTR4 (0.48) | HDAC6 | |
| SCHEMBL14067993 | 0.72 | CNR2 (0.52) | FAAHEPHX2KMT2AMEN1HDAC1 | |
| SCHEMBL1675682 | 0.71 | KMT2A (0.74) | FAAHEPHX2KMT2AMEN1CNR1 | |
| SCHEMBL9727202 | 0.71 | KCNH2 (0.47) | KMT2A | |
| SCHEMBL4401472 | 0.70 | RAB9A (0.61) | FAAHKMT2AMEN1 | |
| SCHEMBL3383913 | 0.69 | KDM4E (0.35) | KMT2AMEN1L3MBTL1 | |
| SCHEMBL1675968 | 0.69 | KMT2A (0.57) | FAAHEPHX2KMT2AMEN1CNR1 | |
| SCHEMBL16292878 | 0.69 | KDM4E (0.38) | KMT2AMEN1L3MBTL1 | |
| SCHEMBL19798433 | 0.69 | EPHX2 (0.67) | EPHX2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1796657-B1 | N-2 ADAMANTANYL-2-PHENOXY-ACETAMIDE DERIVATIVES AS 11-BETA HYDROXYSTEROID DEHYDROGENASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-12-23 | — | — | EP | claimed |