Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 4/20 | 0.55 |
| ▸ | NSD2 | O96028 | 5/20 | 0.53 |
| ▸ | EDNRA | P25101 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4396771 | 1.00 | NPY5R (0.55) | NPY5RNSD2EDNRAMEN1KMT2A | |
| SCHEMBL4445383 | 0.88 | BCL2L1 (0.54) | NPY5RNSD2EDNRAMEN1KMT2A | |
| SCHEMBL13590690 | 0.87 | ACACB (0.57) | NPY5RNSD2EDNRAMEN1KMT2A | |
| SCHEMBL4007555 | 0.82 | NPY5R (0.67) | NPY5RNSD2ALDH1A1NPY1RACACB | |
| SCHEMBL4390192 | 0.82 | NPY5R (0.67) | NPY5RNSD2ALDH1A1NPY1RACACB | |
| SCHEMBL23092875 | 0.77 | EDNRA (0.55) | NPY5RNSD2EDNRAMEN1KMT2A | |
| SCHEMBL29900505 | 0.77 | EDNRA (0.55) | NPY5RNSD2EDNRAMEN1KMT2A | |
| SCHEMBL4443344 | 0.76 | LMNA (0.55) | NSD2EDNRASMN1; SMN2USP30CCR8 | |
| SCHEMBL4397776 | 0.75 | MEN1 (0.68) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4397778 | 0.75 | MEN1 (0.68) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306133-A1 | New Acetyl Coenzyme A Carboxylase (ACC) Inhibitors And Uses In Treatments Of Obesity And Diabetes Mellitus - 087 | ASTRAZENECA AB (SE) | 2009-12-10 | — | — | US | claimed |
| US-20090306133-A1 | New Acetyl Coenzyme A Carboxylase (ACC) Inhibitors And Uses In Treatments Of Obesity And Diabetes Mellitus - 087 | ASTRAZENECA AB (SE) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306133-A1 | New Acetyl Coenzyme A Carboxylase (ACC) Inhibitors And Uses In Treatments Of Obesity And Diabetes Mellitus - 087 | ACACA, ACACB, ACAT1 | NPY5R 890/4885NSD2 2571/4885EDNRA 885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.