Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15391913 | 0.90 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL8187699 | 0.77 | KDM4E (0.35) | ALDH1A1KDM4ETDP1HPRT1 | |
| SCHEMBL17165608 | 0.75 | TDP1 (0.36) | ALDH1A1KMT2AKDM4ETDP1 | |
| SCHEMBL6680764 | 0.71 | HPRT1 (0.38) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL2639252 | 0.68 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL9686102 | 0.68 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL7037922 | 0.67 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL7688731 | 0.66 | MEN1 (0.48) | ALDH1A1MEN1KMT2A | |
| SCHEMBL28746160 | 0.66 | PNP (0.36) | ALDH1A1MEN1KMT2A | |
| SCHEMBL28406873 | 0.65 | ADORA2A (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10175233-B2 | Biomarkers for cardiovascular diseases and methods using the same | METABOLON, INC. (US) | 2019-01-08 | — | — | US | disclosed |
| US-20160178620-A1 | Biomarkers for Pre-Diabetes, Cardiovascular Diseases, and other Metabolic-Syndrome Related Disorders and Methods Using the Same | METABOLON, INC. | 2016-06-23 | — | — | US | disclosed |
| US-9250225-B2 | Biomarkers for insulin resistance and methods using the same | METABOLON, INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-20150005195-A1 | Biomarkers for Pre-Diabetes, Cardiovascular Diseases, and Other Metabolic-Syndrome Related Disorders and Methods Using the Same | METABOLON, INC. | 2015-01-01 | — | — | US | disclosed |
| US-8809008-B2 | Biomarkers for impaired glucose tolerance and methods using the same | METABOLON, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-20130338031-A1 | Biomarkers for Pre-Diabetes, Cardiovascular Diseases, and Other Metabolic-Syndrome Related Disorders and Methods Using the Same | METABOLON, INC. | 2013-12-19 | — | — | US | disclosed |
| EP-2164977-B1 | BIOMARKERS FOR PRE-DIABETES AND METHODS USING THE SAME | METABOLON INC (US) | 2013-10-30 | — | — | EP | disclosed |
| US-8546098-B2 | Biomarkers for monitoring insulin resistance and methods using the same | METABOLON, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20120208215-A1 | Biomarkers for Pre-Diabetes, Cardiovascular Diseases, and Other Metabolic-Syndrome Related Disorders and Methods Using the Same | METABOLON, INC. (US) | 2012-08-16 | — | — | US | disclosed |
| US-8187830-B2 | Method for determining insulin sensitivity with biomarkers | METABOLON, INC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20090155826-A1 | Biomarkers for pre-diabetes, cardiovascular diseases, and other metabolic-syndrome related disorders and methods using the same | METABOLON, INC. (US) | 2009-06-18 | — | — | US | disclosed |