SCHEMBL6680764

SCHEMBL6680764

O=c1nc[nH]c2c1ncn2OP(=O)(O)O

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ HPRT1 P00492 13/20 0.38
▸ ALDH1A1 P00352 2/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ PNP P00491 2/20 0.33
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ ADORA3 P0DMS8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27704099 0.86 HPRT1 (0.35) HPRT1PNP
SCHEMBL29112126 0.85 ALDH1A1 (0.50) HPRT1ALDH1A1KDM4ETDP1MEN1
SCHEMBL389888 0.73 PNP (0.46) HPRT1ALDH1A1PNP
SCHEMBL15391913 0.72 ALDH1A1 (0.35) HPRT1ALDH1A1KDM4ETDP1MEN1
SCHEMBL1820814 0.72 ALDH1A1 (0.49) ALDH1A1PNPHSD17B10
SCHEMBL4397299 0.71 ALDH1A1 (0.35) HPRT1ALDH1A1KDM4ETDP1MEN1
SCHEMBL7037922 0.71 ALDH1A1 (0.36) HPRT1ALDH1A1KDM4ETDP1MEN1
SCHEMBL16513160 0.68 ALDH1A1 (0.34) HPRT1ALDH1A1KDM4ETDP1MEN1
SCHEMBL94916 0.68 ALDH1A1 (0.34) HPRT1ALDH1A1KDM4ETDP1PNP
SCHEMBL9686102 0.68 ALDH1A1 (0.38) HPRT1ALDH1A1KDM4ETDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116144720-B Method for producing pseudouridine by enzyme method 苏州华赛生物工程技术有限公司 2024-05-28 — — CN claimed
CN-116144720-A Method for producing pseudouridine by enzyme method 苏州华赛生物工程技术有限公司 2023-05-23 — — CN claimed
CN-115057837-B Benzofuran compound and preparation method and application thereof 广州润尔眼科生物科技有限公司 2024-11-01 — — CN disclosed
CN-116144720-B Method for producing pseudouridine by enzyme method 苏州华赛生物工程技术有限公司 2024-05-28 — — CN disclosed
CN-117797113-A Sodium mycophenolate tablet and preparation method thereof 卓和药业集团股份有限公司 2024-04-02 — — CN disclosed
WO-2024001067-A1 BENZOFURAN COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 广州润尔眼科生物科技有限公司 2024-01-04 — — WO disclosed
CN-114028334-B Preparation method of immunosuppressant for pulmonary administration 卓和药业集团股份有限公司 2023-08-29 — — CN disclosed
CN-111269890-B Anti-echinococcosis antigen monoclonal antibody hybridoma cell strain, anti-echinococcosis antigen monoclonal antibody and application thereof 新疆畜牧科学院兽医研究所(新疆畜牧科学院动物临床医学研究中心) 2023-07-04 — — CN disclosed
CN-111393399-B Prodrugs of mycophenolic acid and method for preparing same 广州润尔眼科生物科技有限公司 2023-05-30 — — CN disclosed
CN-116144720-A Method for producing pseudouridine by enzyme method 苏州华赛生物工程技术有限公司 2023-05-23 — — CN disclosed
CN-115057837-A Benzofuran compound and preparation method and application thereof 上海英诺富成生物科技有限公司 2022-09-16 — — CN disclosed
CN-1819838-A Methods for in vitro expansion and transdifferentiation of human pancreatic acinar cells into insulin-producing cells BECTON DICKINSON CO (US) 2006-08-16 — — CN disclosed
EP-1468120-A1 CHEMICAL PROTEOMICS MDS Proteomics, Inc. (CA) 2004-10-20 — — EP disclosed
WO-2004070051-A2 CHEMICAL PROTEOMICS MDS PROTEOMICS INC. (CA) 2004-08-19 — — WO disclosed
US-20030166007-A1 Chemical proteomics MDS PROTEOMICS INC. (CA) 2003-09-04 — — US disclosed
US-20030157575-A1 Chemical proteomics PROTANA INC. (CA) 2003-08-21 — — US disclosed
WO-2003064704-A1 CHEMICAL PROTEOMICS MDS PROTEOMICS, INC. (CA) 2003-08-07 — — WO disclosed
US-5521085-A BINDING OF ANTIGENS AND PRODUCING HUMAN IMMUNOGLOBULINS MITSUI TOATSU CHEMICALS, INC. (JP) 1996-05-28 — — US disclosed
EP-0368662-B1 Parent cell lines for producing human hybridomas MITSUI TOATSU CHEMICALS (JP) 1994-09-14 — — EP disclosed
EP-0368662-A2 Parent cell lines for producing human hybridomas MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-05-16 — — EP disclosed
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