SCHEMBL9686102

SCHEMBL9686102

Cn1cnc2c(=O)nc[nH]c21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
PIK3CG P48736 1/20 0.37
PIK3C3 Q8NEB9 1/20 0.37
RAB9A P51151 1/20 0.36
ADORA2A P29274 3/20 0.35
ADORA1 P30542 2/20 0.35
KDM4E B2RXH2 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
HSD17B10 Q99714 1/20 0.33
GDA Q9Y2T3 1/20 0.33
ATAD2 Q6PL18 1/20 0.33
YTHDC1 Q96MU7 1/20 0.33
BRD4 O60885 1/20 0.33
HPRT1 P00492 1/20 0.33
ADORA2B P29275 2/20 0.33
CYP3A4 P08684 2/20 0.33
PMP22 Q01453 2/20 0.33
PIK3CD O00329 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7037922 0.80 ALDH1A1 (0.36) ALDH1A1MEN1KMT2AKDM4ETDP1
SCHEMBL94916 0.77 ALDH1A1 (0.34) ALDH1A1MEN1KMT2AKDM4ETDP1
SCHEMBL16513160 0.77 ALDH1A1 (0.34) ALDH1A1MEN1KMT2AKDM4ETDP1
SCHEMBL2639252 0.77 ALDH1A1 (0.37) ALDH1A1MEN1KMT2AKDM4ETDP1
SCHEMBL612167 0.77 ALDH1A1 (0.34) ALDH1A1MEN1KMT2AKDM4ETDP1
SCHEMBL9010837 0.77 ALDH1A1 (0.35) ALDH1A1MEN1KMT2AKDM4ETDP1
SCHEMBL7168417 0.77 ALDH1A1 (0.34) ALDH1A1MEN1KMT2AKDM4ETDP1
SCHEMBL4404534 0.77 ALDH1A1 (0.34) ALDH1A1MEN1KMT2AKDM4ETDP1
SCHEMBL11270399 0.73 HSD17B10 (0.49) ALDH1A1MEN1KMT2ARAB9AADORA2A
SCHEMBL5523925 0.73 DUSP3 (0.38) ALDH1A1MEN1KMT2AKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3814504-A1 APTAMERS FOR PERSONAL CARE APPLICATIONS The Procter & Gamble Company (US) 2021-05-05 EP claimed
EP-3814505-A1 APTAMERS FOR HAIR CARE APPLICATIONS The Procter & Gamble Company (US) 2021-05-05 EP claimed
EP-3401683-A1 DIAGNOSING METABOLIC DISEASE BY THE USE OF A BIOMARKER Eberhard Karls Universität Tübingen Medizinische Fakultät (DE) 2018-11-14 EP claimed
CN-101065110-A Dried form of aqueous bile acid formulation: preparation and use thereof SEO-HONG YOO (US) 2007-10-31 CN claimed
US-20230272401-A1 COMPOSITIONS FOR FLCN GENE MODULATION AND METHODS THEREOF Genetic Intelligence, Inc 2023-08-31 US disclosed
US-20230167447-A1 Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof GENETIC INTELLIGENCE INC (US) 2023-06-01 US disclosed
EP-4165185-A2 COMPOSITIONS FOR FLCN GENE MODULATION AND METHODS THEREOF Genetic Intelligence, Inc, New York, NY (US) 2023-04-19 EP disclosed
WO-2021252903-A2 COMPOSITIONS FOR FLCN GENE MODULATION AND METHODS THEREOF GENETIC INTELLIGENCE, INC, NEW YORK, NY (US) 2021-12-16 WO disclosed
EP-3814504-A1 APTAMERS FOR PERSONAL CARE APPLICATIONS The Procter & Gamble Company (US) 2021-05-05 EP disclosed
EP-3814505-A1 APTAMERS FOR HAIR CARE APPLICATIONS The Procter & Gamble Company (US) 2021-05-05 EP disclosed
CN-110382709-A Adapter capable of conversion 维尔道应用技术大学 2019-10-25 CN disclosed
EP-3401683-A1 DIAGNOSING METABOLIC DISEASE BY THE USE OF A BIOMARKER Eberhard Karls Universität Tübingen Medizinische Fakultät (DE) 2018-11-14 EP disclosed
CN-101065110-A Dried form of aqueous bile acid formulation: preparation and use thereof SEO-HONG YOO (US) 2007-10-31 CN disclosed
CN-101039699-A Methods and compositions for reducing toxicity of a pharmaceutical compound YOO SEO HONG (US) 2007-09-19 CN disclosed
CN-1942592-A Neisseria gonorrhoeae detection STATE OF QUEENSLAND ACTING THR (AU) 2007-04-04 CN disclosed
US-7192936-B2 Use treating hepatitis C infection optionally with other viricides such as interferons or ribavirin; low toxicity to the host; use of cytosine-based nucleotides or nucleosides having a 2'-trifluoromethyl-ribose moiety which forms a 5'-phosphate or hydroxy moiety in vivo IDENIX PHARMACEUTICALS, INC. (US) 2007-03-20 US disclosed
CN-1122600-A Inhibitors of second messenger cell signaling CELL THERAPEUTICS INC (US) 1996-05-15 CN disclosed
EP-0502690-A2 Cyclopropane derivative Ajinomoto Co., Inc. (JP) 1992-09-09 EP disclosed
CN-1048546-A Substituted imidazo-fused 6 unit heterocycle as angiotensin II antagonism medicine MERCK & CO INC (US) 1991-01-16 CN disclosed
EP-0391592-A1 Process for the enzymatic synthesis of nucleosides THE TEXAS A & M UNIVERSITY SYSTEM (US) 1990-10-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167447-A1 Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof FNIP1, FN1, TNNC1 ALDH1A1 4324/4885MEN1 3817/4885KMT2A 4188/4885
US-20230272401-A1 COMPOSITIONS FOR FLCN GENE MODULATION AND METHODS THEREOF TARDBP, FUS, RBM17 ALDH1A1 4065/4885MEN1 4364/4885KMT2A 3496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.