Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3967989 | 0.94 | THRA (0.48) | THRATHRBPTGS2ALOX5PPARA | |
| SCHEMBL4405740 | 0.94 | THRA (0.48) | THRATHRBPTGS2ALOX5PPARA | |
| SCHEMBL258595 | 0.90 | THRA (0.40) | THRATHRBPTGS2ALOX5PPARA | |
| SCHEMBL11533893 | 0.87 | THRA (0.39) | THRATHRBPTGS2ALOX5PPARA | |
| SCHEMBL10349365 | 0.86 | THRA (0.38) | THRATHRBPTGS2ALOX5PPARA | |
| SCHEMBL8600591 | 0.85 | THRA (0.47) | THRATHRBPTGS2ALOX5PPARA | |
| SCHEMBL3477747 | 0.85 | THRA (0.47) | THRATHRBPTGS2ALOX5PPARA | |
| SCHEMBL284750 | 0.85 | THRA (0.47) | THRATHRBPTGS2ALOX5PPARA | |
| SCHEMBL5552764 | 0.84 | L3MBTL1 (0.41) | PTGS2 | |
| SCHEMBL8375499 | 0.82 | THRA (0.45) | THRATHRBPTGS2ALOX5PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054491-A1 | GREASE COMPOSITION FOR CONSTANT VELOCITY JOINTS | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 2009-05-06 | — | — | EP | disclosed |
| US-20080234153-A1 | LUBRICATING OIL COMPOSITION | NIPPON OIL CORPORATION (JP) | 2008-09-25 | — | — | US | disclosed |
| WO-2007129775-A1 | GREASE COMPOSITION FOR CONSTANT VELOCITY JOINTS | SHOWA SHELL SEKIYU K.K. (JP) | 2007-11-15 | — | — | WO | disclosed |