SCHEMBL258595

SCHEMBL258595

CCCCc1ccccc1OP(=O)(Oc1ccccc1CCCC)Sc1ccccc1CCCC

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.40
THRB P10828 1/20 0.40
PTGS2 P35354 5/20 0.38
ALOX5 P09917 1/20 0.36
PPARA Q07869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL284750 0.94 THRA (0.47) THRATHRBPTGS2ALOX5PPARA
SCHEMBL3477747 0.94 THRA (0.47) THRATHRBPTGS2ALOX5PPARA
SCHEMBL8600591 0.94 THRA (0.47) THRATHRBPTGS2ALOX5PPARA
SCHEMBL258521 0.91 HTR1A (0.38) THRATHRBPTGS2
SCHEMBL4397512 0.90 THRA (0.41) THRATHRBPTGS2ALOX5PPARA
SCHEMBL11533893 0.86 THRA (0.39) THRATHRBPTGS2ALOX5PPARA
SCHEMBL10349365 0.85 THRA (0.38) THRATHRBPTGS2ALOX5PPARA
SCHEMBL4405740 0.84 THRA (0.48) THRATHRBPTGS2ALOX5PPARA
SCHEMBL3967989 0.84 THRA (0.48) THRATHRBPTGS2ALOX5PPARA
SCHEMBL5607684 0.83 L3MBTL1 (0.41) PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11946012-B2 Lubricating oil composition SHELL USA, INC. (US) 2024-04-02 US disclosed
US-20230002695-A1 LUBRICATING OIL COMPOSITION SHELL USA, INC. 2023-01-05 US disclosed
US-11254890-B2 Lubricant composition TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2022-02-22 US disclosed
WO-2021079976-A1 LUBRICATING OIL COMPOSITION FOR AUTOMOTIVE GEARS SHELL LUBRICANTS JAPAN K.K. (JP) 2021-04-29 WO disclosed
US-20210054299-A1 LUBRICANT COMPOSITION TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2021-02-25 US disclosed
EP-2980194-B1 LUBRICANT OIL COMPOSITION IDEMITSU KOSAN CO (JP) 2020-04-01 EP disclosed
EP-2855645-B1 LUBRICATING OIL COMPOSITION SHELL INT RESEARCH (NL) 2019-08-14 EP disclosed
EP-2104728-B1 LUBRICATING OIL COMPOSITION SHELL INT RESEARCH (NL) 2018-10-24 EP disclosed
US-9410106-B2 Lubricating oil composition IDEMITSU KOSAN CO., LTD. (JP) 2016-08-09 US disclosed
EP-2980194-A1 LUBRICANT OIL COMPOSITION Idemitsu Kosan Co., Ltd (JP) 2016-02-03 EP disclosed
US-20070032391-A1 Refrigerating machine oil composition NIPPON OIL CORPORATION (JP) 2007-02-08 US disclosed
EP-1741771-A1 METALWORKING FLUID Nippon Oil Corporation (JP) 2007-01-10 EP disclosed
EP-1740679-A2 LUBRICANT AND FUEL COMPOSITIONS CONTAINING HYDROXY POLYCARBOXYLIC ACID ESTERS CHEMTURA CORPORATION (US) 2007-01-10 EP disclosed
EP-1734103-A1 LUBRICATING OIL COMPOSITION FOR INDUSTRIAL MACHINERY AND EQUIPMENT Nippon Oil Corporation (JP) 2006-12-20 EP disclosed
EP-1721957-A1 GREASE COMPOSITION FOR CONSTANT VELOCITY JOINT Nippon Oil Corporation (JP) 2006-11-15 EP disclosed
EP-1702972-A1 METALWORKING FLUID Nippon Oil Corporation (JP) 2006-09-20 EP disclosed
WO-2005087904-A2 LUBRICANT AND FUEL COMPOSITIONS CONTAINING HYDROXY POLYCARBOXYLIC ACID ESTERS CHEMTURA CORPORATION (US) 2005-09-22 WO disclosed
EP-1500694-A1 GREASE COMPOSITION Nippon Oil Corporation (JP) 2005-01-26 EP disclosed
US-20040209786-A1 comprises mineral oil, and phosphate compound selected a zinc dithiophosphate having hydrocarbon group, a triaryl phosphate, and triaryl thiophosphate; for electric motors; improved insulation, cooling and lubricity NIPPON OIL CORPORATION (JP) 2004-10-21 US disclosed
EP-1405897-A1 TRANSMISSION OIL COMPOSITION FOR AUTOMOBILE Nissan Motor Co., Ltd. (JP) 2004-04-07 EP disclosed