Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CD44 | P16070 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437233 | 0.89 | NR4A2 (0.51) | NR4A2KDM4ETDP1NCF1MAPT | |
| SCHEMBL441437 | 0.83 | MAPT (0.57) | NR4A2MAPTHSP90AA1HSP90AB1MEN1 | |
| SCHEMBL438207 | 0.83 | MAPT (0.53) | NR4A2MAPTHSP90AA1HSP90AB1MEN1 | |
| SCHEMBL11543194 | 0.81 | NR4A2 (0.51) | NR4A2KDM4ETDP1MAPTL3MBTL1 | |
| SCHEMBL11637772 | 0.78 | KDM4E (0.50) | NR4A2KDM4ETDP1MAPTL3MBTL1 | |
| SCHEMBL11544558 | 0.76 | NR4A2 (0.46) | NR4A2KDM4ETDP1MAPTL3MBTL1 | |
| SCHEMBL439579 | 0.74 | NR4A2 (0.65) | NR4A2KDM4ETDP1NCF1MAPT | |
| SCHEMBL438980 | 0.74 | NR4A2 (1.00) | NR4A2KDM4ETDP1NCF1MAPT | |
| SCHEMBL439768 | 0.74 | NR4A2 (0.65) | NR4A2KDM4ETDP1NCF1MAPT | |
| SCHEMBL436991 | 0.74 | NOS3 (0.41) | NR4A2MAPTHSP90AB1TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |