Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437696 | 0.83 | KDM4E (0.50) | KDM4EGPR3ALDH1A1GLAHPGD | |
| SCHEMBL271715 | 0.79 | BIRC5 (0.59) | ALPLBIRC5KDM4EGPR3ALDH1A1 | |
| Bromide SCHEMBL7788733 | 0.78 | BIRC5 (0.58) | ALPLBIRC5KDM4EGPR3ALDH1A1 | |
| SCHEMBL4709550 | 0.74 | BIRC5 (0.51) | ALPLBIRC5KDM4EGPR3ALDH1A1 | |
| SCHEMBL442137 | 0.73 | HTT (0.49) | KDM4EALDH1A1GLASMN1; SMN2ACHE | |
| SCHEMBL438932 | 0.73 | ACHE (0.46) | ACHEHTTBCHE | |
| Quinoline SCHEMBL28218277 | 0.72 | ALDH1A1 (0.63) | ALPLBIRC5KDM4EALDH1A1CASP1 | |
| SCHEMBL18318196 | 0.70 | SMN1; SMN2 (0.44) | ALPLBIRC5KDM4EGPR3SMN1; SMN2 | |
| Acetic Acid SCHEMBL28150882 | 0.69 | MGAM (0.57) | ALPLBIRC5KDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL16506046 | 0.69 | KDM4E (0.47) | KDM4EGPR3ALDH1A1GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |