Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
| ▸ | PTGES | O14684 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442137 | 0.86 | HTT (0.49) | ACHEHTTBACE1TNFBCHE | |
| SCHEMBL437952 | 0.81 | ACHE (0.45) | ACHEPTGESHTTBACE1PDPK1 | |
| SCHEMBL20476253 | 0.81 | ACHE (0.45) | ACHEPTGESHTTBACE1EGFR | |
| SCHEMBL19890459 | 0.81 | PTGES (0.46) | PTGESHTTTNFALKNT5E | |
| SCHEMBL30074851 | 0.81 | ACHE (0.45) | ACHEPTGESHTTBACE1EGFR | |
| SCHEMBL23037563 | 0.79 | ACHE (0.43) | ACHEPTGESHTTBACE1PDPK1 | |
| SCHEMBL442268 | 0.79 | ACHE (0.46) | ACHETNFPDPK1BCHEGRIN1 | |
| SCHEMBL22323491 | 0.79 | HTT (0.41) | ACHEPTGESHTTBACE1EGFR | |
| SCHEMBL438239 | 0.79 | ACHE (0.46) | ACHEBCHEGRIN1GRIN2ANR4A2 | |
| SCHEMBL31728137 | 0.75 | PTGES (0.41) | ACHEPTGESBACE1EGFRPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |