Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 5/20 | 0.46 |
| ▸ | ACHE | P22303 | 5/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438932 | 0.86 | ACHE (0.46) | HTTTNFBCHEACHEGRIN1 | |
| SCHEMBL21143332 | 0.81 | TNF (0.50) | HTTTNFSMN1; SMN2NT5EKDM4E | |
| SCHEMBL439464 | 0.81 | NR4A2 (0.55) | BCHEACHEGRIN1GRIN2ACYP1A2 | |
| SCHEMBL16224287 | 0.81 | BCHE (0.45) | HTTBCHEACHEGRIN1GRIN2A | |
| SCHEMBL18449315 | 0.81 | TNF (0.50) | HTTTNFSMN1; SMN2NT5EKDM4E | |
| SCHEMBL438613 | 0.81 | BCHE (0.45) | HTTBCHEACHEGRIN1GRIN2A | |
| SCHEMBL30509817 | 0.81 | TNF (0.50) | HTTTNFSMN1; SMN2NT5EKDM4E | |
| SCHEMBL21143331 | 0.79 | TNF (0.48) | HTTTNFSMN1; SMN2NT5EKDM4E | |
| SCHEMBL21190488 | 0.79 | TNF (0.55) | HTTTNFSMN1; SMN2NT5EKDM4E | |
| SCHEMBL20073053 | 0.79 | HTT (0.49) | HTTTNFBCHEACHEGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |