Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.42 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.36 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1922555 | 0.81 | GPR119 (0.48) | GPR119TEAD1TEAD3BCHEMAOA | |
| SCHEMBL2561511 | 0.80 | GPR119 (0.61) | GPR119 | |
| SCHEMBL4403110 | 0.80 | MAOB (0.44) | GPR119BCHEMAOAACHEMAOB | |
| SCHEMBL13534689 | 0.78 | GPR119 (0.49) | GPR119 | |
| SCHEMBL1296310 | 0.77 | GPR119 (0.63) | GPR119 | |
| SCHEMBL1295563 | 0.73 | GPR119 (0.47) | GPR119BCHEMAOAACHEMAOB | |
| SCHEMBL12103493 | 0.73 | ITGB3 (0.53) | — | |
| SCHEMBL12283385 | 0.73 | GPR119 (0.42) | GPR119BCHEMAOAACHEMAOB | |
| SCHEMBL1841877 | 0.73 | GPR119 (0.47) | GPR119 | |
| SCHEMBL1839393 | 0.73 | GPR119 (0.46) | GPR119TEAD1TEAD3BCHEMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321308-B1 | PIPERIDINE GPCR AGONISTS | PROSIDION LTD (GB) | 2012-05-09 | — | — | EP | disclosed |