Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439423 | 0.83 | HAVCR2 (0.36) | HAVCR2LMNAPOLBMAPTMEN1 | |
| SCHEMBL436942 | 0.81 | HAVCR2 (0.41) | HAVCR2MAPTMEN1NPC1GAA | |
| SCHEMBL439785 | 0.78 | HAVCR2 (0.68) | HAVCR2LMNAPOLBMAPTMEN1 | |
| SCHEMBL441707 | 0.76 | HAVCR2 (0.63) | HAVCR2LMNASMN1; SMN2DYRK1AALDH1A1 | |
| SCHEMBL442157 | 0.76 | HAVCR2 (0.36) | HAVCR2DYRK1A | |
| SCHEMBL437847 | 0.76 | CCR1 (0.42) | HAVCR2LMNAPOLBMAPTNPC1 | |
| SCHEMBL441974 | 0.73 | HAVCR2 (0.38) | HAVCR2MAPTMEN1KMT2ADYRK1A | |
| SCHEMBL437767 | 0.72 | HAVCR2 (0.46) | HAVCR2POLBMAPTMEN1KMT2A | |
| SCHEMBL441422 | 0.72 | HAVCR2 (0.46) | HAVCR2SMN1; SMN2NR4A2ACHE | |
| SCHEMBL442075 | 0.72 | HAVCR2 (0.46) | HAVCR2LMNAPOLBMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |