Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15251307 | 0.98 | CA4 (0.34) | CA4 | |
| SCHEMBL917184 | 0.96 | CA4 (0.35) | CA4 | |
| SCHEMBL6310261 | 0.96 | CA4 (0.35) | CA4 | |
| Potassium Ion SCHEMBL18173761 | 0.96 | CA12 (0.32) | CA4 | |
| SCHEMBL3765845 | 0.94 | CA4 (0.30) | CA4 | |
| Ammonia Solution, Strong SCHEMBL10493453 | 0.94 | CA4 (0.34) | CA4 | |
| SCHEMBL2319007 | 0.94 | CA4 (0.39) | CA4 | |
| SCHEMBL320905 | 0.85 | CA4 (0.31) | CA4 | |
| SCHEMBL1832568 | 0.81 | — | — | |
| Ethylene Glycol SCHEMBL9640310 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090304628-A1 | STABILIZED PHARMACEUTICAL FORMULATIONS THAT CONTAIN THE INTERFERONS GAMMA AND ALPHA IN SYNERGISTIC PROPORTIONS | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CU) | 2009-12-10 | — | — | US | claimed |