Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6310261 | 0.98 | CA4 (0.35) | CA4 | |
| SCHEMBL917184 | 0.98 | CA4 (0.35) | CA4 | |
| SCHEMBL15251307 | 0.96 | CA4 (0.34) | CA4 | |
| Ammonia Solution, Strong SCHEMBL10493453 | 0.96 | CA4 (0.34) | CA4 | |
| Potassium Ion SCHEMBL18173761 | 0.94 | CA12 (0.32) | CA4 | |
| SCHEMBL4398018 | 0.94 | CA4 (0.31) | CA4 | |
| SCHEMBL3765845 | 0.92 | CA4 (0.30) | CA4 | |
| SCHEMBL320905 | 0.87 | CA4 (0.31) | CA4 | |
| Ethylene Glycol SCHEMBL9640310 | 0.82 | — | — | |
| SCHEMBL1832568 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1643864-B1 | AIDING OF COGNITIVE FUNCTION | UNILEVER NV (NL) | 2011-08-10 | — | — | EP | disclosed |
| US-20070036870-A1 | Aiding of cognitive function | CONOPCO, INC. D/B/A UNILEVER | 2007-02-15 | — | — | US | disclosed |
| EP-1716766-A1 | Aiding of cognitive function | UNILEVER N.V. (NL) | 2006-11-02 | — | — | EP | disclosed |
| EP-1643864-A1 | AIDING OF COGNITIVE FUNCTION | UNILEVER N.V. (NL) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005013724-A1 | AIDING OF COGNITIVE FUNCTION | UNILEVER N.V. (NL) | 2005-02-17 | — | — | WO | disclosed |