SCHEMBL4398068

SCHEMBL4398068

[CH2]S(=O)(=O)c1cccc(C)c1

nearest known ligand 0.63

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.55
ACHE P22303 1/20 0.48
MEN1 O00255 2/20 0.47
ALDH1A1 P00352 3/20 0.45
FBP1 P09467 9/20 0.44
MAPT P10636 2/20 0.44
HPGD P15428 1/20 0.44
MMP2 P08253 1/20 0.44
EDNRA P25101 1/20 0.42
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29468572 0.81 KMT2A (0.59) KMT2AACHEMEN1ALDH1A1FBP1
SCHEMBL822302 0.81 KMT2A (0.59) KMT2AACHEMEN1ALDH1A1FBP1
SCHEMBL8264434 0.80 KMT2A (0.53) KMT2AACHEMEN1ALDH1A1FBP1
SCHEMBL12808 0.79 KMT2A (0.57) KMT2AACHEMEN1ALDH1A1FBP1
SCHEMBL15607666 0.79 KMT2A (0.57) KMT2AACHEMEN1ALDH1A1MAPT
SCHEMBL330676 0.79 KMT2A (0.57) KMT2AACHEMEN1ALDH1A1FBP1
Hydrochloric Acid SCHEMBL11279258 0.79 KMT2A (0.57) KMT2AACHEMEN1ALDH1A1FBP1
Ethylene SCHEMBL28384942 0.78 ALDH1A1 (0.53) KMT2AACHEMEN1ALDH1A1FBP1
SCHEMBL4619061 0.77 KMT2A (0.55) KMT2AACHEMEN1ALDH1A1FBP1
SCHEMBL6832061 0.77 ALDH1A1 (0.57) KMT2AACHEMEN1ALDH1A1FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090306376-A1 OPTICAL RECORDING MEDIUM AND COMPOUND USED FOR THE SAME MITSUI CHEMICALS, INC. (JP) 2009-12-10 US disclosed
US-7405030-B2 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2008-07-29 US disclosed
EP-1930339-A2 Imide compound MITSUI CHEMICALS, INC. (JP) 2008-06-11 EP disclosed
US-20070259151-A1 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2007-11-08 US disclosed
US-7259260-B2 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2007-08-21 US disclosed
US-20070054084-A1 Optical recording medium and compound used for the same MITSUI CHEMICALS, INC. (JP) 2007-03-08 US disclosed
EP-1672626-A1 OPTICAL RECORDING MEDIUM AND COMPOUND USED IN THE OPTICAL RECORDING MEDIUM Mitsui Chemicals, Inc. (JP) 2006-06-21 EP disclosed
US-20050208425-A1 Imide compound and optical recording media made by using the same YAMAMOTO CHEMICALS, INC. (JP) 2005-09-22 US disclosed
EP-1445115-A1 IMIDE COMPOUNDS AND OPTICAL RECORDING MEDIA MADE BY USING THE SAME Mitsui Chemicals, Inc. (JP) 2004-08-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090306376-A1 OPTICAL RECORDING MEDIUM AND COMPOUND USED FOR THE SAME CACNA1B, KCNN4, KCNN2 KMT2A 3032/4885ACHE 197/4885MEN1 979/4885
US-20050208425-A1 Imide compound and optical recording media made by using the same CRY1, MTNR1A, TRPA1 KMT2A 1745/4885ACHE 1282/4885MEN1 18/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.