Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2175968 | 0.98 | BCHE (0.46) | BCHEGRIN1GRIN2AKDM4EACHE | |
| SCHEMBL4399006 | 0.83 | GGPS1 (0.44) | BCHEGRIN1GRIN2AKDM4EGGPS1 | |
| Hydrochloric Acid SCHEMBL2177623 | 0.82 | HDAC1 (0.46) | BCHEGRIN1GRIN2AKDM4EGGPS1 | |
| SCHEMBL21490429 | 0.81 | TSHR (0.44) | KDM4ETSHRHDAC1CYP2D6HDAC4 | |
| Bromide SCHEMBL20544414 | 0.79 | KDM4E (0.58) | BCHEKDM4EACHEHDAC1HDAC4 | |
| SCHEMBL28051020 | 0.76 | GGPS1 (0.34) | KDM4EGGPS1CYP2D6 | |
| SCHEMBL294104 | 0.75 | LMNA (0.44) | KDM4EACHE | |
| Bromide SCHEMBL7696012 | 0.75 | CYP2D6 (0.55) | BCHEKDM4EACHETSHRHDAC1 | |
| SCHEMBL4401483 | 0.74 | BCHE (0.50) | BCHEGRIN1GRIN2AKDM4EACHE | |
| SCHEMBL295339 | 0.73 | TSHR (0.41) | KDM4EGGPS1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178678-B2 | Bis-quaternary ammonium salts and methods for modulating neuronal nicotinic acetylcholine receptors | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2012-05-15 | — | — | US | disclosed |
| US-20100069432-A1 | Bis-Quaternary Ammonium Salts and Methods for Modulating Neuronal Nicotinic Acetylcholine Receptors | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069432-A1 | Bis-Quaternary Ammonium Salts and Methods for Modulating Neuronal Nicotinic Acetylcholine Receptors | CHRNA2, CHRNA5, CHRNA4 | BCHE 39/4885GRIN1 29/4885GRIN2A 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.