Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MDM4 | O15151 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5078613 | 0.84 | HPGD (0.50) | NPC1SMN1; SMN2HPGDTDP1ALDH1A1 | |
| SCHEMBL8444052 | 0.80 | F2R (0.45) | NPC1SMN1; SMN2HTTHPGDGAA | |
| SCHEMBL13292672 | 0.77 | PRNP (0.36) | NPC1SMN1; SMN2HTTHPGDGAA | |
| SCHEMBL13304624 | 0.76 | SMN1; SMN2 (0.48) | NPC1SMN1; SMN2HTTHPGDGAA | |
| SCHEMBL5634500 | 0.76 | L3MBTL1 (0.52) | NPC1SMN1; SMN2HTTHPGDGAA | |
| SCHEMBL4399333 | 0.74 | NPC1 (0.56) | NPC1SMN1; SMN2HTTHPGDGAA | |
| SCHEMBL442079 | 0.74 | ATM (0.51) | NPC1SMN1; SMN2GAAALDH1A1ATM | |
| SCHEMBL13851050 | 0.73 | ATM (0.37) | NPC1HTTGAAALDH1A1ATM | |
| SCHEMBL17999737 | 0.73 | ALDH1A1 (0.35) | NPC1SMN1; SMN2HTTHPGDGAA | |
| SCHEMBL12798649 | 0.73 | CYP1A2 (0.48) | NPC1SMN1; SMN2HPGDTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11228309-A | — | — | None | — | — | JP | disclosed |
| JP-H11228309-A | PLANT DISEASE-PREVENTING AGENT COMPOSITION | MITSUI CHEM INC | 1999-08-24 | — | — | JP | disclosed |
| US-5869427-A | Substituted thiophene derivative and plant disease control agent comprising the same as active ingredient | MITSUI CHEMICALS, INC. (JP) | 1999-02-09 | — | — | US | disclosed |
| EP-0841336-A1 | Substituted thiopene derivative and plant disease control agent comprising the same as active ingredient | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1998-05-13 | — | — | EP | disclosed |