SCHEMBL439955

SCHEMBL439955

CC[SiH](CC)[Zr](Cl)(Cl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.35
HTR6 P50406 1/20 0.35
SIGMAR1 Q99720 6/20 0.34
KDM4E B2RXH2 2/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
CHRM2 P08172 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD2 P14416 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
NFKB1 P19838 1/20 0.33
CHRM3 P20309 1/20 0.33
SLC6A2 P23975 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33
HRH1 P35367 1/20 0.33
DRD3 P35462 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL439531 0.91 HTR6 (0.32) HTR2AHTR6SIGMAR1
SCHEMBL437852 0.89 HTR6 (0.33) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL60272 0.84 HTR6 (0.33) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL437345 0.83 HTR6 (0.31) HTR2AHTR6
SCHEMBL437054 0.83 HTR6 (0.31) HTR2AHTR6SIGMAR1
SCHEMBL7632416 0.83 HTR2A (0.39) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL1143732 0.82 HTR2A (0.32) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL7101679 0.81 SLC22A2 (0.31)
SCHEMBL846366 0.81 RET (0.37) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL441993 0.80 SIGMAR1 (0.32) HTR2AHTR6SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8871885-B2 Ethylene-a-olefin copolymer and molded article SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-10-28 US disclosed
US-8501891-B2 Ethylene-α-olefin copolymer and molded article SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-08-06 US disclosed
US-8299194-B2 Ethylene-α-olefin copolymer and article SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-30 US disclosed
US-20120123006-A1 RESIN COMPOSITION FOR CROSSLINKING/FOAM MOLDING, CROSSLINKED MOLDED FOAM, MEMBER FOR FOOTWEAR, AND FOOTWEAR SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-17 US disclosed
US-20120065351-A1 ETHYLENE-ALPHA-OLEFIN COPOLYMER AND MOLDED ARTICLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-15 US disclosed
US-20120065352-A1 ETHYLENE-A-OLEFIN COPOLYMER AND ARTICLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-15 US disclosed
US-20110136994-A1 OLEFIN POLYMERIZATION CATALYST AND PRODUCTION PROCESS OF OLEFIN POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-09 US disclosed
US-20110040059-A1 ETHYLENE-a-OLEFIN COPOLYMER AND MOLDED ARTICLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-02-17 US disclosed
US-20100310799-A1 ETHYLENE-a-OLEFIN COPOLYMER AND MOLDED ARTICLE SUMITOMO CHEMICAL COMPANY, LIMITED 2010-12-09 US disclosed
US-20100305292-A1 ETHYLENE-a-OLEFIN COPOLYMER AND MOLDED ARTICLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-12-02 US disclosed
EP-0881232-B1 Catalyst for olefin polymerization and process for the production of an olefin polymer TOSOH CORP (JP) 2005-03-16 EP disclosed
EP-0727443-B1 Catalyst for olefin polymerization and process for producing olefin polymers TOSOH CORP (JP) 2001-01-17 EP disclosed
US-6034187-A Catalyst for olefin polymerization and process for production of olefin polymer TOSOH CORPORATION (JP) 2000-03-07 US disclosed
EP-0881232-A1 Catalyst for olefin polymerization and process for production of olefin polymer TOSOH CORPORATION (JP) 1998-12-02 EP disclosed
US-5807938-A Catalyst for olefin polymerization and process for producing olefin polymers TOSOH CORPORATION (JP) 1998-09-15 US disclosed
US-5712365-A Process for producing ethylene alpha-olefin copolymer TOSOH CORPORATION (JP) 1998-01-27 US disclosed
EP-0730003-B1 Polypropylene resin composition and molded product TOSOH CORP (JP) 1997-12-29 EP disclosed
US-5608008-A ETHYLENE-A-OLEFIN COPOLYMER ELASTOMER TOSOH CORPORATION (JP) 1997-03-04 US disclosed
EP-0730003-A1 Polypropylene resin composition and molded product Tosoh Corporation (JP) 1996-09-04 EP disclosed
EP-0727443-A1 Catalyst for olefin polymerization and process for producing olefin polymers Tosoh Corporation (JP) 1996-08-21 EP disclosed