SCHEMBL60272

SCHEMBL60272

C[SiH](C)[Zr](Cl)(Cl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.33
HTR2A P28223 2/20 0.32
SIGMAR1 Q99720 2/20 0.31
BRD4 O60885 1/20 0.30
CCL2 P13500 1/20 0.30
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
CHRM2 P08172 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CHRM1 P11229 1/20 0.30
DRD2 P14416 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
NFKB1 P19838 1/20 0.30
CHRM3 P20309 1/20 0.30
SLC6A2 P23975 1/20 0.30
HTR2C P28335 1/20 0.30
ADRA1A P35348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27454170 0.89
SCHEMBL6916127 0.88 SLC22A2 (0.30)
SCHEMBL439955 0.84 HTR2A (0.35) HTR6HTR2ASIGMAR1KDM4ELMNA
SCHEMBL6915555 0.84 HTR6 (0.32) HTR6HTR2ASIGMAR1
SCHEMBL7198906 0.84
SCHEMBL439185 0.83 SIGMAR1 (0.32) SIGMAR1BRD4CCL2
SCHEMBL6448432 0.83
SCHEMBL437852 0.83 HTR6 (0.33) HTR6HTR2ASIGMAR1KDM4ELMNA
SCHEMBL216045 0.83 SIGMAR1 (0.31) SIGMAR1
SCHEMBL6910229 0.83 HTR6 (0.31) HTR6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1602 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12351657-B2 Controlling long-chain branch content with dual activator-supports CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2025-07-08 US claimed
CN-116020416-B Method for removing metallocene catalyst 中国石油化工股份有限公司 2025-06-17 CN claimed
CN-116589614-B Method for preparing COF-supported olefin polymerization catalyst 浙江大学衢州研究院 2025-05-27 CN claimed
US-20250129487-A1 PRODUCTION METHOD FOR AMMONIA AND PRODUCTION DEVICE NISSAN CHEMICAL CORPORATION (JP) 2025-04-24 US claimed
CN-116023532-B Preparation method of saturated metallocene poly alpha-olefin 中国石油化工股份有限公司 2025-02-11 CN claimed
US-20250011481-A1 CONTROLLING LONG-CHAIN BRANCH CONTENT WITH DUAL ACTIVATOR-SUPPORTS CHEVRON PHILLIPS CHEMICAL COMPANY LP 2025-01-09 US claimed
WO-2025000320-A1 METHOD FOR PREPARING POLYOLEFIN BY MEANS OF CASCADE POLYMERIZATION 浙江大学衢州研究院 2025-01-02 WO claimed
US-12122857-B2 Controlling long-chain branch content with dual activator-supports CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2024-10-22 US claimed
US-20230295813-A1 AMMONIA PRODUCTION METHOD AND AMMONIA PRODUCTION APPARATUS NISSAN CHEMICAL CORPORATION (JP) 2023-09-21 US claimed
CN-116685609-A Method for preparing supported olefin polymerization catalyst, catalyst obtained by method and application of catalyst 浙江大学 2023-09-01 CN claimed
US-5708090-A Process for the preparation of a polypropylene molding composition HOECHST AKTIENGESELLSCHAFT (DE) 1998-01-13 US claimed
EP-0610852-B1 Process for preparing cyclo-olefin polymers HOECHST AG (DE) 1997-05-07 EP claimed
US-5616747-A Process for the preparation of bridged, chiral metallocene catalysts of the bisindenyl type HOECHST AKTIENGESELLSCHAFT (DE) 1997-04-01 US claimed
US-5583192-A POLYMERIZING A CYCLOOLEFIN AND AN OLEFIN IN THE PRESENCE OF A METALLOCENE CATALYST HOECHST AKTIENGESELLSCHAFT (DE) 1996-12-10 US claimed
WO-1996035730-A1 AMORPHOUS OLEFIN CO/TER-POLYMERS OPTATECH CORPORATION (FI) 1996-11-14 WO claimed
WO-1996034002-A1 ENHANCED SYNTHESIS OF RACEMIC METALLOCENES ALBEMARLE CORPORATION (US) 1996-10-31 WO claimed
US-5556997-A Enhanced synthesis of racemic metallocenes ALBEMARLE CORPORATION (US) 1996-09-17 US claimed
US-5545829-A Process for preparing cycloolefin copolymers HOECHST AKTIENGESELLSCHAFT (DE) 1996-08-13 US claimed
EP-0284708-B1 Metallocene catalyst systems for olefin polymerization having a silicon hydrocarbyl bridge. FINA TECHNOLOGY (US) 1996-01-31 EP claimed
EP-0574597-A1 Process for the preparation of bridged, chiral metallocene catalysts of the bisindenyl type HOECHST AKTIENGESELLSCHAFT (DE) 1993-12-22 EP claimed