SCHEMBL846366

SCHEMBL846366

CC[Zr](Cl)(Cl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RET P07949 1/20 0.37
HTR2A P28223 2/20 0.36
HTR6 P50406 1/20 0.36
SIGMAR1 Q99720 6/20 0.35
KDM4E B2RXH2 2/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
CHRM2 P08172 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD2 P14416 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
NFKB1 P19838 1/20 0.33
CHRM3 P20309 1/20 0.33
SLC6A2 P23975 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33
HRH1 P35367 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7899799 0.83 HTR6 (0.33) RETHTR2AHTR6SIGMAR1KDM4E
Hydrochloric Acid SCHEMBL7107235 0.81 SIGMAR1 (0.35) RETHTR2AHTR6SIGMAR1KDM4E
SCHEMBL439955 0.81 HTR2A (0.35) RETHTR2AHTR6SIGMAR1KDM4E
SCHEMBL28440009 0.80 HTR2A (0.37) RETHTR2AHTR6SIGMAR1KDM4E
SCHEMBL3380394 0.79 HTR2A (0.35) RETHTR2AHTR6SIGMAR1KDM4E
SCHEMBL7641692 0.79 BRD4 (0.33) RETHTR2AHTR6SIGMAR1KDM4E
SCHEMBL1921550 0.78 SIGMAR1 (0.35) RETHTR2AHTR6SIGMAR1KDM4E
SCHEMBL7621928 0.78 HTR2A (0.33) RETHTR2AHTR6SIGMAR1KDM4E
SCHEMBL7643746 0.78 HTR2A (0.37) RETHTR2AHTR6SIGMAR1KDM4E
SCHEMBL4479570 0.78 HTR2A (0.33) RETHTR2AHTR6SIGMAR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160251464-A1 ETHYLENE-BASED QUATERPOLYMER HAVING LOW GLASS TRANSITION TEMPERATURE AND PREPARATION METHOD THEREOF KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2016-09-01 US claimed
US-8987398-B2 Ethylene-based terpolymer having high elasticity and preparation method thereof KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2015-03-24 US claimed
US-20130096269-A1 ETHYLENE-BASED TERPOLYMER HAVING HIGH ELASTICITY AND PREPARATION METHOD THEREOF KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2013-04-18 US claimed
US-11859316-B2 Process for the production of fibers TOTALENERGIES ONETECH BELGIUM (BE) 2024-01-02 US disclosed
US-20210047755-A1 Fibers and Nonwovens Including a Propylene Random Copolymer, and Processes for Producing the Fibers and Nonwovens TOTALENERGIES ONETECH BELGIUM (BE) 2021-02-18 US disclosed
US-20190193351-A1 Extrusion Blow-Molded Articles and Process for Their Production TOTAL RES & TECHNOLOGY FELUY (BE) 2019-06-27 US disclosed
US-10272624-B2 Extrusion blow-molded articles and process for their production TOTAL RESEARCH & TECHNOLOGY FELUY (BE) 2019-04-30 US disclosed
EP-3140266-B1 USE OF A METALLOCENE CATALYST TO PRODUCE A POLYALPHA-OLEFIN TOTAL RES & TECHNOLOGY FELUY (BE) 2018-05-16 EP disclosed
EP-2880099-B1 POLYALPHAOLEFINS PREPARED USING MODIFIED SALAN CATALYST COMPOUNDS AND PROCESS FOR PREPARING SAID POLYOLEFINS EXXONMOBIL CHEMICAL PATENTS INC (US) 2018-01-03 EP disclosed
EP-2880096-B1 PROCESS FOR PREPARING POLYALPHAOLEFINS USING MODIFIED SALAN CATALYST COMPOUNDS AND POLYALPHAOLEFINS PREPARED THEREWITH EXXONMOBIL CHEMICAL PATENTS INC (US) 2018-01-03 EP disclosed
US-9803034-B2 Highly functional graft copolymer and method for preparing the same KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2017-10-31 US disclosed
US-20080177121-A1 Process to produce high viscosity fluids EXXONMOBIL CHEMICAL PATENTS INC. 2008-07-24 US disclosed
US-20070043248-A1 Process to produce low viscosity poly-alpha-olefins EXXONMOBIL CHEMICAL PATENTS INC. 2007-02-22 US disclosed
EP-0818458-B1 TRANSITION METAL COMPOUND, POLYMERIZATION CATALYST FOR OLEFINS, AND PROCESS FOR PRODUCING OLEFINIC POLYMERS IDEMITSU KOSAN CO (JP) 2004-02-25 EP disclosed
US-6414102-B2 PREPARED USING SINGLE SITE METALLOCENE CATALYST THE PENN STATE RESEARCH FOUNDATION 2002-07-02 US disclosed
US-6339135-B1 AS POLYMERIZATION CATALYST IDEMITSU KOSAN CO., LTD. (JP) 2002-01-15 US disclosed
US-20010047069-A1 Linear copolymers of alpha-olefins and divinylbenzene having narrow molecular weight and composition distributions, graft copolymers derived therefrom, and process for preparing same PENN STATE RESEARCH FOUNDATION, THE 2001-11-29 US disclosed
US-6265493-B1 GRAFT POLYMERS THE PENN STATE RESEARCH FOUNDATION 2001-07-24 US disclosed
WO-2001007489-A1 LINEAR ALPHA-OLEFIN/DIVINYLBENZENE COPOLYMERS AND GRAFT THE PENN STATE RESEARCH FOUNDATION (US) 2001-02-01 WO disclosed
EP-0818458-A1 TRANSITION METAL COMPOUND, POLYMERIZATION CATALYST FOR OLEFINS, AND PROCESS FOR PRODUCING OLEFINIC POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-01-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070043248-A1 Process to produce low viscosity poly-alpha-olefins AP1M1, AP3D1, AP3M1 RET 4412/4885HTR2A 3084/4885HTR6 1615/4885
US-20080177121-A1 Process to produce high viscosity fluids SCO2, POLI, TAOK1 RET 1817/4885HTR2A 570/4885HTR6 981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.