Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.33 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL726736 | 0.86 | TDP1 (0.41) | TDP1SMN1; SMN2ALDH1A1HTR1AADRA1D | |
| SCHEMBL1240959 | 0.84 | THRB (0.40) | THRBTGM2TEAD1TEAD3TDP1 | |
| Acrylic Acid SCHEMBL1344846 | 0.76 | SLC6A3 (0.36) | AKT1ALDH1A1LMNA | |
| SCHEMBL9589101 | 0.75 | MEN1 (0.37) | TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9587807 | 0.73 | TDP1 (0.39) | TDP1TSHR | |
| Acrylic Acid SCHEMBL27040911 | 0.72 | THRB (0.43) | THRBTGM2TDP1AKT1KMT2A | |
| Acrylic Acid SCHEMBL7078870 | 0.71 | MTNR1A (0.42) | THRBTGM2TDP1AKT1KMT2A | |
| SCHEMBL10600797 | 0.71 | CYP1A2 (0.39) | TDP1ALDH1A1MTNR1AMTNR1BRAB9A | |
| SCHEMBL671115 | 0.71 | TDP1 (0.38) | TDP1TSHRCHRM1 | |
| Acrylic Acid SCHEMBL27803178 | 0.71 | MTNR1A (0.45) | THRBTGM2TDP1AKT1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306422-A1 | OLIGOMERIC URETHANE ACRYLATES, THEIR PREPARATION AND USE | BASF COATINGS AG (DE) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306422-A1 | OLIGOMERIC URETHANE ACRYLATES, THEIR PREPARATION AND USE | NOX1, CBR1, NOXO1 | THRB 3533/4885TGM2 4253/4885TEAD1 4805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.