Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.43 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.37 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | TTK | P33981 | 4/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11918141 | 0.76 | ITGB3 (0.44) | GPR119HRH3TTK | |
| SCHEMBL1838268 | 0.75 | GPR119 (0.48) | GPR119BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL13162332 | 0.73 | KMT2A (0.45) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL13534689 | 0.72 | GPR119 (0.49) | GPR119HRH3 | |
| SCHEMBL2394333 | 0.72 | GPR119 (0.44) | GPR119BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL4403111 | 0.72 | ITGB3 (0.42) | GPR119 | |
| SCHEMBL2214693 | 0.71 | GPR119 (0.48) | GPR119BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL2392621 | 0.71 | GPR119 (0.47) | GPR119BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL2392624 | 0.71 | GPR119 (0.47) | GPR119BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL13534631 | 0.70 | GPR119 (0.62) | GPR119BMPR1BBMPR1ATGFBR1ACVRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321308-B9 | PIPERIDINE GPCR AGONISTS | PROSIDION LTD (GB) | 2012-08-08 | — | — | EP | disclosed |
| EP-2321308-B1 | PIPERIDINE GPCR AGONISTS | PROSIDION LTD (GB) | 2012-05-09 | — | — | EP | disclosed |