Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.57 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 2/20 | 0.53 |
| ▸ | CES1 | P23141 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6459498 | 0.96 | ALDH1A1 (0.58) | AKR1C3CYP2C8CYP2C9KDM4EALDH1A1 | |
| SCHEMBL29530654 | 0.96 | ALDH1A1 (0.58) | AKR1C3CYP2C8CYP2C9KDM4EALDH1A1 | |
| SCHEMBL7915439 | 0.93 | CYP2C8 (0.60) | AKR1C3CYP2C8CYP2C9KDM4EALDH1A1 | |
| SCHEMBL11483510 | 0.90 | MEN1 (0.53) | AKR1C3CYP2C8CYP2C9KDM4EALDH1A1 | |
| SCHEMBL18940467 | 0.90 | ALDH1A1 (0.49) | AKR1C3CYP2C8CYP2C9KDM4EALDH1A1 | |
| SCHEMBL17009656 | 0.89 | MAPT (0.57) | AKR1C3CYP2C8CYP2C9KDM4EALDH1A1 | |
| SCHEMBL1667151 | 0.88 | ALDH1A1 (0.59) | AKR1C3CYP2C8CYP2C9KDM4EALDH1A1 | |
| SCHEMBL12337417 | 0.85 | ALDH1A1 (0.61) | AKR1C3CYP2C8CYP2C9KDM4EALDH1A1 | |
| SCHEMBL8785619 | 0.85 | KDM4E (0.61) | AKR1C3CYP2C8CYP2C9KDM4EALDH1A1 | |
| SCHEMBL11699182 | 0.85 | CES2 (0.49) | AKR1C3CYP2C8CYP2C9KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242162-B2 | Sensor group attachec to imide of aromatictetracarboxylic dianhydride; aromatic core may be anthracene, phenanthrene, perylene, or benzo[e]pyrene; sensor groups include crown ethers, aryl amines, porphyrins, and phenylboronic acid; detecting nitroaromatic explosives and chemical warfare agents | OHIO AEROSPACE INSTITUTE (US) | 2012-08-14 | — | — | US | disclosed |
| US-8242162-B2 | Sensor group attachec to imide of aromatictetracarboxylic dianhydride; aromatic core may be anthracene, phenanthrene, perylene, or benzo[e]pyrene; sensor groups include crown ethers, aryl amines, porphyrins, and phenylboronic acid; detecting nitroaromatic explosives and chemical warfare agents | OHIO AEROSPACE INSTITUTE (US) | 2012-08-14 | — | — | US | disclosed |
| US-8242162-B2 | Sensor group attachec to imide of aromatictetracarboxylic dianhydride; aromatic core may be anthracene, phenanthrene, perylene, or benzo[e]pyrene; sensor groups include crown ethers, aryl amines, porphyrins, and phenylboronic acid; detecting nitroaromatic explosives and chemical warfare agents | OHIO AEROSPACE INSTITUTE (US) | 2012-08-14 | — | — | US | disclosed |
| US-8173276-B2 | Materials for electroluminescence and the utilization thereof | MERCK PATENT GMBH (DE) | 2012-05-08 | — | — | US | disclosed |
| US-20100102305-A1 | MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF | MERCK PATENT GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
| US-7659540-B2 | Materials for electroluminescence and the utilization thereof | MERCK PATENT GMBH (DE) | 2010-02-09 | — | — | US | disclosed |
| US-20080242870-A1 | FLUORESCENT AROMATIC SENSORS AND THEIR METHODS OF USE | OHIO AEROSPACE INSTITUTE (US) | 2008-10-02 | — | — | US | disclosed |
| US-20080242870-A1 | FLUORESCENT AROMATIC SENSORS AND THEIR METHODS OF USE | OHIO AEROSPACE INSTITUTE (US) | 2008-10-02 | — | — | US | disclosed |
| US-20080242870-A1 | FLUORESCENT AROMATIC SENSORS AND THEIR METHODS OF USE | OHIO AEROSPACE INSTITUTE (US) | 2008-10-02 | — | — | US | disclosed |
| US-20070080343-A1 | New materials for electroluminescence and the utilization thereof | MERCK PATENT GMBH (DE) | 2007-04-12 | — | — | US | disclosed |
| US-6974855-B1 | Polyimides by photochemical cyclopolymerization | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2005-12-13 | — | — | US | disclosed |
| EP-1501830-A1 | 7-ARYL-3,9-DIAZABICYCLO[3.3.1]NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES | Actelion Pharmaceuticals Ltd. (CH) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003093267-A1 | 7-ARYL-3,9-DIAZABICYCLO(3.3.1)NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES | ACTELION PHARMACEUTICALS LTD (CH) | 2003-11-13 | — | — | WO | disclosed |
| US-6593389-B1 | Diels-Alder cyclopolymerization of a photochemically generated bisdiene with dienophiles, such as bismaleimides, trismaleimides and mixtures thereof with maleimide end-caps. Irradiation of one or more diketones produces two distinct | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION | 2003-07-15 | — | — | US | disclosed |
| US-6534589-B1 | Catalytic curing and polymerization of episulfide compound in presence of phenolic compound | MITSUBISHI GAS CHEMICAL COMPANY INC. (JP) | 2003-03-18 | — | — | US | disclosed |
| US-6486230-B1 | Polyesters by photochemical cyclopolymerization | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION | 2002-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242870-A1 | FLUORESCENT AROMATIC SENSORS AND THEIR METHODS OF USE | AHR, PAH, ALK | AKR1C3 2809/4885CYP2C8 982/4885CYP2C9 855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.