SCHEMBL1667151

SCHEMBL1667151

Cc1ccc(C(=O)c2ccccc2)cc1C(=O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.59
ATM Q13315 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
KDM4E B2RXH2 1/20 0.55
PTGS2 P35354 1/20 0.54
SRD5A2 P31213 1/20 0.52
CDC25A P30304 1/20 0.52
CDC25B P30305 1/20 0.52
HSD17B10 Q99714 1/20 0.52
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
HTT P42858 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
NPC1 O15118 3/20 0.50
POLB P06746 2/20 0.50
AKR1C3 P42330 2/20 0.50
CYP2C8 P10632 1/20 0.50
CYP2C9 P11712 1/20 0.50
MITF O75030 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10782252 0.93 HTT (0.64) ALDH1A1ATMTDP1L3MBTL1KDM4E
SCHEMBL27406781 0.89 KDM4E (0.66) ALDH1A1KDM4EPTGS2SRD5A2CDC25A
SCHEMBL4400929 0.88 AKR1C3 (0.57) ALDH1A1ATMTDP1L3MBTL1KDM4E
SCHEMBL8756315 0.87 ALDH1A1 (0.50) ALDH1A1ATMTDP1L3MBTL1KDM4E
SCHEMBL7481641 0.87 TDP1 (0.52) ALDH1A1ATMTDP1L3MBTL1KDM4E
SCHEMBL29060736 0.87 ALDH1A1 (0.62) ALDH1A1TDP1HSD17B10CES2CES1
SCHEMBL12337417 0.86 ALDH1A1 (0.61) ALDH1A1ATMTDP1L3MBTL1KDM4E
SCHEMBL15759866 0.86 ATM (0.60) ALDH1A1ATMTDP1L3MBTL1PTGS2
SCHEMBL7915439 0.86 CYP2C8 (0.60) ALDH1A1ATMTDP1L3MBTL1KDM4E
SCHEMBL305558 0.85 NPSR1 (0.60) ALDH1A1PTGS2CES2CES1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108060308-B Method and device for separating lithium from lithium-containing solution 中南大学 2020-01-03 CN claimed
CN-115215728-A High-energy-efficiency preparation method of alkali metal alkoxide 赢创功能性解决方案有限公司 2022-10-21 CN disclosed
CN-108060308-B Method and device for separating lithium from lithium-containing solution 中南大学 2020-01-03 CN disclosed
EP-1830228-B1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2015-08-05 EP disclosed
EP-2808736-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-12-03 EP disclosed
US-8802353-B2 Compound for resist and radiation-sensitive composition specification MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-08-12 US disclosed
EP-2662727-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-11-13 EP disclosed
US-8350096-B2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-01-08 US disclosed
US-20130004896-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION SPECIFICATION ECHIGO MASATOSHI (JP) 2013-01-03 US disclosed
US-20110165516-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION ECHIGO MASATOSHI 2011-07-07 US disclosed
US-7919223-B2 Polyphenol compound synthesized by condensation between aromatic ketone or aldehyde and a phenol; acid-amplified, non-polymeric resist; highly sensitive to KrF excimer lasers, extreme ultraviolet rays, electron beams, X-rays; resist patterns with high resolution, high heat, etch resistance MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2011-04-05 US disclosed
US-20080113294-A1 Compound for Resist and Radiation-Sensitive Composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2008-05-15 US disclosed
EP-1830228-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-09-05 EP disclosed
US-6458972-B1 THERMAL CLEAVAGE OF MACROCYCLIC ESTERS IN THE PRESENCE OF A THERMOSTABLE BENZENE DERIVATIVE HAARMANN & REIMER GMBH (DE) 2002-10-01 US disclosed
US-20020095045-A1 Process for the preparation of macrocyclic esters SYMRISE GMBH & CO., KG (DE) 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110165516-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION XRCC6, XRCC5, KISS1R ALDH1A1 1170/4885ATM 267/4885TDP1 1518/4885
US-20020095045-A1 Process for the preparation of macrocyclic esters CYP3A4, CYP4A11, CASP14 ALDH1A1 2102/4885ATM 1826/4885TDP1 2295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.