SCHEMBL7915439

SCHEMBL7915439

Cc1cc(C)c(C(=O)c2ccccc2)cc1C(=O)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C8 P10632 1/20 0.60
CYP2C9 P11712 1/20 0.60
AKR1C3 P42330 2/20 0.55
KDM4E B2RXH2 1/20 0.55
ALDH1A1 P00352 2/20 0.55
ATM Q13315 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
SRD5A2 P31213 1/20 0.52
CES2 O00748 2/20 0.52
CES1 P23141 2/20 0.52
HPGD P15428 2/20 0.51
GAA P10253 2/20 0.50
MAPT P10636 1/20 0.50
PTGS2 P35354 1/20 0.50
POLB P06746 1/20 0.50
MEN1 O00255 1/20 0.50
USP2 O75604 1/20 0.50
KMT2A Q03164 1/20 0.50
KEAP1 Q14145 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29530654 0.94 ALDH1A1 (0.58) CYP2C8CYP2C9AKR1C3KDM4EALDH1A1
SCHEMBL6459498 0.94 ALDH1A1 (0.58) CYP2C8CYP2C9AKR1C3KDM4EALDH1A1
SCHEMBL4400929 0.93 AKR1C3 (0.57) CYP2C8CYP2C9AKR1C3KDM4EALDH1A1
SCHEMBL1667151 0.86 ALDH1A1 (0.59) CYP2C8CYP2C9AKR1C3KDM4EALDH1A1
SCHEMBL11698701 0.85 CES2 (0.47) CYP2C8CYP2C9AKR1C3KDM4EALDH1A1
SCHEMBL11483510 0.84 MEN1 (0.53) CYP2C8CYP2C9AKR1C3KDM4EALDH1A1
SCHEMBL18940467 0.84 ALDH1A1 (0.49) CYP2C8CYP2C9AKR1C3KDM4EALDH1A1
SCHEMBL12337417 0.83 ALDH1A1 (0.61) CYP2C8CYP2C9AKR1C3KDM4EALDH1A1
SCHEMBL17009656 0.83 MAPT (0.57) CYP2C8CYP2C9AKR1C3KDM4EALDH1A1
SCHEMBL11699182 0.83 CES2 (0.49) CYP2C8CYP2C9AKR1C3KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed