Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20993084 | 0.81 | — | — | |
| SCHEMBL20057288 | 0.79 | BRD4 (0.37) | CYP1B1KDM4EALDH1A1CYP3A4GAA | |
| SCHEMBL24939703 | 0.79 | CREBBP (0.39) | KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL16484921 | 0.78 | CYP1B1 (0.35) | CYP1B1POLBALDH1A1CYP3A4HPGD | |
| SCHEMBL5495765 | 0.78 | CYP1B1 (0.35) | CYP1B1POLBALDH1A1CYP3A4HPGD | |
| SCHEMBL22601621 | 0.76 | LMNA (0.32) | CYP1B1LMNA | |
| SCHEMBL1920814 | 0.73 | HTR1A (0.37) | POLB | |
| SCHEMBL4397980 | 0.71 | ALDH1A1 (0.32) | ALDH1A1LMNA | |
| SCHEMBL5970129 | 0.71 | CNR2 (0.31) | — | |
| SCHEMBL16708705 | 0.70 | TP53 (0.44) | POLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496270-B1 | ZIRCONIUM-RADIOLABELED, CYSTEINE ENGINEERED ANTIBODY CONJUGATES | HOFFMANN LA ROCHE (CH) | 2018-01-31 | — | — | EP | disclosed |
| EP-2793928-B1 | PROCESS FOR PURIFYING A SAMPLE OF H38C2 ANTIBODY | PFIZER (US) | 2017-03-15 | — | — | EP | disclosed |
| WO-2013093720-A2 | ANTI-DIABETIC COMPOUNDS | PFIZER INC. (US) | 2013-06-27 | — | — | WO | disclosed |
| WO-2012059873-A2 | ANTI-DIABETIC COMPOUNDS | COVX TECHNOLOGIES IRELAND, LTD. (IE) | 2012-05-10 | — | — | WO | disclosed |