SCHEMBL5495765

SCHEMBL5495765

O=CC1CCC(CN2C(=O)C=CC2=O)CC1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1B1 Q16678 4/20 0.35
MGLL Q99685 5/20 0.34
FAAH O00519 3/20 0.34
ALDH1A1 P00352 3/20 0.34
LMNA P02545 2/20 0.34
MAPT P10636 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
GMNN O75496 1/20 0.34
THPO P40225 1/20 0.34
BLM P54132 1/20 0.34
PMP22 Q01453 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
HSP90AA1 P07900 1/20 0.33
TLR9 Q9NR96 1/20 0.33
TP53 P04637 1/20 0.33
PKM P14618 1/20 0.33
HPGD P15428 1/20 0.33
XBP1 P17861 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16484921 1.00 CYP1B1 (0.35) CYP1B1MGLLFAAHALDH1A1LMNA
SCHEMBL485615 0.86 MGLL (0.44) CYP1B1MGLLFAAHALDH1A1LMNA
SCHEMBL1920814 0.79 HTR1A (0.37) POLB
SCHEMBL4400934 0.78 CYP1B1 (0.34) CYP1B1ALDH1A1LMNAHPGDCYP3A4
SCHEMBL20365061 0.78 CYP1B1 (0.44) CYP1B1MGLLFAAHALDH1A1LMNA
SCHEMBL5531964 0.77 HPGD (0.38) CYP1B1MGLLFAAHALDH1A1LMNA
SCHEMBL1707544 0.77 MGLL (0.41) CYP1B1MGLLFAAHALDH1A1LMNA
SCHEMBL4761414 0.77 MGLL (0.46) CYP1B1MGLLFAAHALDH1A1LMNA
SCHEMBL10147918 0.76 MGLL (0.38) CYP1B1MGLLFAAHALDH1A1LMNA
SCHEMBL1275809 0.76 CYP1B1 (0.45) CYP1B1MGLLFAAHALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240240025-A1 Blue-Excitable Water-Solvated Polymeric Dyes BECTON, DICKINSON AND COMPANY 2024-07-18 US disclosed
CN-117642185-A Improved CD30 targeting antibody drug conjugates and uses thereof 路德维希-马克西米利安慕尼黑大学 2024-03-01 CN disclosed
EP-4328270-A2 ULTRAVIOLET ABSORBING POLYMERIC DYES AND METHODS FOR USING THE SAME Becton, Dickinson and Company (US) 2024-02-28 EP disclosed
US-11912876-B2 Blue-excitable water-solvated polymeric dyes BECTON, DICKINSON AND COMPANY (US) 2024-02-27 US disclosed
US-11874278-B2 Reagents for directed biomarker signal amplification SIRIGEN II LIMITED (GB) 2024-01-16 US disclosed
CN-116917484-A Ligase fusion proteins and uses thereof 启德医药科技(苏州)有限公司 2023-10-20 CN disclosed
US-20230288428-A1 Ultraviolet Absorbing Polymeric Dyes and Methods for Using the Same BECTON, DICKINSON AND COMPANY 2023-09-14 US disclosed
US-20230273215-A1 Novel Reagents for Directed Biomarker Signal Amplification SIRIGEN, INC. 2023-08-31 US disclosed
US-11732138-B2 Deep ultraviolet-excitable water-solvated polymeric dyes BECTON, DICKINSON AND COMPANY (US) 2023-08-22 US disclosed
US-20230251264-A1 Novel Reagents for Directed Biomarker Signal Amplification SIRIGEN, INC. 2023-08-10 US disclosed
US-9758625-B2 Polymeric BODIPY dyes and methods for using the same BECTON, DICKINSON AND COMPANY (US) 2017-09-12 US disclosed
US-9719998-B2 Ultraviolet absorbing polymeric dyes and methods for using the same BECTON DICKINSON AND COMPANY (US) 2017-08-01 US disclosed
WO-2017105927-A1 POLYMERIC DYE RATIOMETRIC SENSOR FOR ANALYTE DETECTION AND METHODS OF USING THE SAME BECTON, DICKINSON AND COMPANY (US) 2017-06-22 WO disclosed
US-20170174892-A1 PHOTOSTABLE FLUORESCENT POLYMERIC TANDEM DYES INCLUDING LUMINESCENT METAL COMPLEXES BECTON, DICKINSON AND COMPANY 2017-06-22 US disclosed
WO-2017105928-A1 PHOTOSTABLE FLUORESCENT POLYMERIC TANDEM DYES INCLUDING LUMINESCENT METAL COMPLEXES BECTON, DICKINSON AND COMPANY (US) 2017-06-22 WO disclosed
EP-1572242-B1 IMMUNOCONJUGATES WITH AN INTRACELLULARLY-CLEAVABLE LINKAGE IMMUNOMEDICS INC (US) 2014-04-16 EP disclosed
US-7364739-B2 Haemophilus influenzae lipopolysaccharide inner-core oligosaccharide epitopes as vaccines for the prevention of Haemophilus influenzae infections NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2008-04-29 US disclosed
US-20070207952-A1 Long Acting Biologically Active Conjugates SEQUOIA PHARMACEUTICALS (US) 2007-09-06 US disclosed
EP-1620120-A2 LONG ACTING BIOLOGICALLY ACTIVE CONJUGATES Sequoia Pharmaceuticals (US) 2006-02-01 EP disclosed
WO-2004085505-A2 LONG ACTING BIOLOGICALLY ACTIVE CONJUGATES SEQUOIA PHARMACEUTICALS, INC. (US) 2004-10-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11874278-B2 Reagents for directed biomarker signal amplification RNGTT, CAPG, CA14 CYP1B1 4874/4885MGLL 4274/4885FAAH 4217/4885
US-20070207952-A1 Long Acting Biologically Active Conjugates ALB, ACE, VIP CYP1B1 4050/4885MGLL 3789/4885FAAH 2574/4885
US-20230251264-A1 Novel Reagents for Directed Biomarker Signal Amplification RNGTT, CAPG, CD2BP2 CYP1B1 4870/4885MGLL 4322/4885FAAH 4147/4885
US-20230273215-A1 Novel Reagents for Directed Biomarker Signal Amplification RNGTT, CAPG, CD2BP2 CYP1B1 4870/4885MGLL 4322/4885FAAH 4147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.