Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4408042 | 0.99 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1MAPK1CYP3A4CYP1A2 | |
| SCHEMBL4403275 | 0.92 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1MAPK1CYP3A4CYP1A2 | |
| SCHEMBL4402457 | 0.91 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1MAPK1CYP3A4CYP1A2 | |
| SCHEMBL4403280 | 0.86 | ALDH1A1 (0.32) | ALDH1A1L3MBTL1MAPK1CYP3A4CYP1A2 | |
| SCHEMBL4402463 | 0.81 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1MAPK1CYP3A4CYP1A2 | |
| SCHEMBL4402448 | 0.81 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1MAPK1CYP3A4CYP1A2 | |
| SCHEMBL4408037 | 0.79 | MGAM (0.30) | TSHR | |
| SCHEMBL4403290 | 0.72 | CETP (0.43) | ALDH1A1L3MBTL1MAPK1CYP3A4CYP1A2 | |
| SCHEMBL19152589 | 0.71 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1MAPK1CYP3A4TSHR | |
| SCHEMBL4403270 | 0.71 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1MAPK1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168741-B2 | Chelating silicon-based polymers | JOINT INTELLECTUAL PROPERTY POLICY OF MCMASTER UNIVERSITY (CA) | 2012-05-01 | — | — | US | disclosed |
| US-20090118456-A1 | CHELATING SILICON-BASED POLYMERS | MCMASTER UNIVERSITY (CA) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118456-A1 | CHELATING SILICON-BASED POLYMERS | SRM, SMURF1, SLC39A14 | ALDH1A1 4478/4885L3MBTL1 3625/4885MAPK1 4503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.